/*safety*/
/*Header*/
#metastatic-safety #main-nav nav.cmp-navigation ul.cmp-navigation__group li.cmp-navigation__item--level-0:nth-child(3) ul.cmp-navigation__dropdownmenu li a.sub-active-link,
#metastatic-safety #main-nav nav.cmp-navigation ul.cmp-navigation__group li.cmp-navigation__item--level-0:nth-child(3) ul.cmp-navigation__dropdownmenu li:hover a.sub-active-link {
    font-weight: 700;
    font-family: "Roboto Condensed";
    border-bottom: none;
    background: url(/content/dam/intelligentcontent/brands/imfinzi-hcp/us/en/hcc/efficacy/desktop/white-arrow.png) no-repeat bottom center;
}

#metastatic-safety #main-container {
    margin-top: 83px;
    background: url(/content/dam/intelligentcontent/brands/imfinzi-hcp/us/en/dmmr-endometrial-cancer/images/desktop/new-bg-design.png) no-repeat #ecf1f6;
    background-position-y: -84px;
    background-size: 100%;
    font-family: 'Ubuntu';
    padding-bottom: 81px;
}

#metastatic-safety h1 {
    font-size: 38px;
    line-height: normal;
    color: #003865;
    max-width: 722px;
    margin: 0 auto;
    font-weight: 700;
    padding: 70px 0 30px;
    max-width: 850px;
    width: 100%;
    padding: 78px 0 31px;
}

#metastatic-safety #white-container {
    max-width: 950px;
    background: #ffffff;
    margin: 0 auto;
}

#metastatic-safety .content-container {
    max-width: 722px;
    margin: 0 auto;
    max-width: 850px;
    width: 100%;
}

#metastatic-safety .cmp-text {
    font-family: 'Ubuntu';
    padding: 0;
}

#metastatic-safety .section-heading {
    border-top: 1px solid #00618b;
    margin-bottom: 25px;
}

#metastatic-safety .section-heading p {
    max-width: 722px;
    margin: 0 auto;
    padding-top: 11px;
    height: 24px;
    max-width: 850px;
    width: 100%;
}

#metastatic-safety .section-heading span {
    color: #ffffff;
    background: #003865;
    font-size: 15px;
    line-height: normal;
    font-weight: 700;
    padding: 6px 7px;
    border-bottom-left-radius: 20px;
    border-bottom-right-radius: 20px;
    padding: 11px 17.4px;
}

#metastatic-safety #main-container h2 {
    font-size: 24px;
    line-height: 28px;
    color: #003865;
    font-weight: 500;
    /* padding: 10px 0 10px; */
    margin-top: 23px;
    margin-bottom: 10px;
    margin: 38px 0 42px;
}

#metastatic-safety .box-image .data-compare {
    justify-content: space-between;
    display: flex;
    align-items: center;
    width: 100%;
    max-width: 520px;
    margin: 50px auto 29px;
    margin-left: 16%;
}

#metastatic-safety .box-image .data-compare p {
    margin: 0 0 10px;
    text-align: center;
    font-size: 16px;
    line-height: 18px;
    font-weight: 400;
}

#metastatic-safety .box-image .data-compare .data-num {
    font-size: 42px;
    line-height: 48px;
    font-weight: 700;
    margin-bottom: 0;
    font-size: 61px;
    line-height: normal;
}

#metastatic-safety .box-image .data-compare .data-grey-txt p {
    color: #555454;
}

#metastatic-safety .box-image .data-compare .data-teal-txt p {
    color: #007a6d;
}

#metastatic-safety .box-image .data-compare .data-ver-line {
    background: #003865;
    width: 1px;
    height: 114px;
    bottom: 15px;
    position: relative;
}

#metastatic-safety .box-image {
    border: 0.5px solid #03315D;
    max-width: 680px;
    margin: 36px auto;
    padding: 20px;
    max-width: 850px;
    width: 100%;
    border-radius: 32px;
}

#metastatic-safety p.box-heading {
    font-size: 18px;
    line-height: normal;
    letter-spacing: 0.03px;
    color: #003466;
    font-weight: 700;
    position: relative;
    padding: 0 6px 0 30px;
    background: #ffffff;
    margin-top: -31px;
    width: fit-content;
    padding: 0 15px 0 6px;
    margin-left: 21px;
    margin-right: 21px;
}

#metastatic-safety .box-image.key-table sup,
#metastatic-safety .list-sec ul.arrow-list sup,
#metastatic-safety .footnote-section .footnotes sup,
#metastatic-safety #main-container #wrapper-container-2 h2 sup,
#metastatic-safety #main-container #wrapper-container-3 h2 sup {
    font-size: 75%;
    top: -.5em;
    line-height: 0;
    position: relative;
    vertical-align: baseline;
}

#metastatic-safety .box-image.key-table .ast-sup {
    top: -4px;
    position: relative;
}

#metastatic-safety .box-image.key-table .data-num sup {
    top: -8px;
}

#metastatic-safety p.box-heading:before {
    /* content: ''; */
    background: url(/content/dam/intelligentcontent/brands/imfinzi-hcp/us/en/dmmr-endometrial-cancer/images/mobile/callout-arrow.svg) no-repeat;
    width: 61px;
    height: 36px;
    position: absolute;
    left: -42px;
    top: -9px;
}

#metastatic-safety .box-image.key-table.key-table1 p.box-heading {
    margin-top: -30px;
}

#metastatic-safety p.footnotes {
    font-size: 13px;
    line-height: 18px;
    color: #4A4A4A;
    font-family: 'Ubuntu';
    text-indent: 0;
    margin-left: 0px;
    margin-bottom: 5px;
    position: relative;
    font-weight: 300;
    letter-spacing: 0.07px;
    color: #555;
    font-weight: 400;
    margin-bottom: 0;
}

#metastatic-safety p.footnotes .ast-footnote {
    margin-left: -7px;
}

#metastatic-safety .single-footnote,
#metastatic-safety .double-footnote {
    margin-left: -5px;
    font-family: 'Ubuntu', sans-serif;
}

#metastatic-safety .key-table p.box-heading:before {
    top: -8px;
}

#metastatic-safety table {
    border-collapse: collapse;
    border-spacing: 0;
    width: 100%;
    margin: 0 auto;
}

#metastatic-safety .key-table1 .table-block td:first-child,
#metastatic-safety .key-table2 .table-block2 td:first-child,
#metastatic-safety .key-table3 .table-block3 td:first-child {
    max-width: 240px;
}

#metastatic-safety .key-table1 .table-block tr.span-row td,
#metastatic-safety .key-table2 .table-block2 tr.span-row td,
#metastatic-safety .key-table3 .table-block3 tr.span-row td {
    border-right: none;
}

#metastatic-safety .key-table1 .table-block tr.span-row td:first-child,
#metastatic-safety .key-table2 .table-block2 tr.span-row td:first-child,
#metastatic-safety .key-table3 .table-block3 tr.span-row td:first-child {
    font-weight: 700;
}

#metastatic-safety .key-table1 .table-block .f-teal,
#metastatic-safety .key-table2 .table-block2 .f-teal,
#metastatic-safety .key-table3 .table-block3 .f-teal {
    color: #007a6d;
    letter-spacing: 0.038px;
    font-weight: 700;
}
#metastatic-safety .key-table2 .table-block2 .f-teal{
    letter-spacing: -0.223px;
    padding: 7px 10px;
    font-size: 19.005px;
}

#metastatic-safety .key-table1 .table-block .teal-cell,
#metastatic-safety .key-table2 .table-block2 .teal-cell,
#metastatic-safety .key-table3 .table-block3 .teal-cell {
    background: transparent;
    color: #007a6d;
    font-weight: 700;
}

#metastatic-safety .key-table1 .table-block td,
#metastatic-safety .key-table1 .table-block th,
#metastatic-safety .key-table2 .table-block2 td,
#metastatic-safety .key-table2 .table-block2 th,
#metastatic-safety .key-table3 .table-block3 td,
#metastatic-safety .key-table3 .table-block3 th {
    font-family: 'Ubuntu';
    font-size: 19.491px;
    padding: 4px;
    line-height: normal;
    letter-spacing: -0.152px;
    /*padding:7px 10px;
    letter-spacing: -0.223px;
    font-size: 19.005px;
    line-height: 20.064px;*/
}
#metastatic-safety .key-table2 .table-block2 td{
    font-family: 'Ubuntu';
    /*font-size: 19.491px;
    padding: 4px;
    line-height: normal;
    letter-spacing: -0.152px;*/
    padding:7px 10px;
    letter-spacing: -0.223px;
    font-size: 19.005px;
    line-height: 20.064px;
}
#metastatic-safety .key-table1 .table-block,
#metastatic-safety .key-table2 .table-block2,
#metastatic-safety .key-table3 .table-block3 {
    margin: 35px auto 5px;
    max-width: 615px;
    max-width: 810px;
}

#metastatic-safety td,
#metastatic-safety th {
    text-align: center;
    font-weight: 400;
    font-size: 14px;
    line-height: 14px;
    color: #4e5055;
    border-right: 1px solid rgba(102, 161, 214, 0.5);
    border-bottom: 1px solid rgba(102, 161, 214, 0.5);
    padding: 10px 0;
    white-space: nowrap;
}

#metastatic-safety th {
    font-weight: 700;
    border-top: none;
    padding: 10px 0;
}

#metastatic-safety td:first-child {
    text-align: left;
    border-left: none
}

#metastatic-safety .box-image.key-table.key-table2 th:first-child {
    text-align: left;
    border-left: none;
    border-bottom: none;
}

#metastatic-safety td:last-child,
#metastatic-safety th:last-child {
    border-right: none
}

#metastatic-safety table tr:last-child td {
    border-bottom: none;
}

#metastatic-safety .footnotes.footnote-last {
    margin-bottom: 50px;
    margin-top: 30px;
}

#metastatic-safety .box-image.key-table.key-table2 .box-heading {
    max-width: 562px;
    width: 100%;
    margin-top: -30px;
}

#metastatic-safety #wrapper-container-1 .list-sec {
    margin: 20px auto;
}

#metastatic-safety .arrow-list {
    list-style-type: none;
    padding-left: 32px;
    margin-bottom: 10px;
    margin-top: 0;
}

#metastatic-safety .arrow-list li {
    font-size: 16px;
    line-height: 20px;
    margin-bottom: 17px;
    font-family: "Ubuntu", sans-serif;
    font-weight: 300;
    position: relative;
    color: #4A4A4A;
    color: #555;
    font-weight: 400;
}

#metastatic-safety .arrow-list li:before {
    content: '';
    background: url(/content/dam/intelligentcontent/brands/imfinzi-hcp/us/en/nsclc/metatastic/safety/images/list-arrow.svg) no-repeat;
    position: absolute;
    width: 26px;
    height: 13px;
    top: 4px;
    left: -33px;
    background-size: 26px 13px;
}

#metastatic-safety .arrow-list.first-list .fw-bold {
    font-weight: 700;
}

/*Hot links*/
#metastatic-safety .safety-page-content {
    max-width: 680px;
    margin: 0 auto;
    width: 100%;
}

#metastatic-safety .switch-section {
    margin: 0px auto;
    display: flex;
    width: 100%;
    justify-content: space-between;
    position: relative;
    /* margin-top: 25px; */
}

#metastatic-safety .switch-section a {
    color: #003865;
    font-weight: 700;
    font-size: 16px;
    line-height: 20px;
    padding: 30px 50px;
    font-family: 'Ubuntu';
}

#metastatic-safety .switch-section a:before {
    background: url(/content/dam/intelligentcontent/brands/imfinzi-hcp/us/en/biliary-tract-cancer/about-btcs/images/page-switch-icon.png) no-repeat;
    content: '';
    width: 32px;
    height: 32px;
    position: absolute;
    left: 0;
    top: 22px;
}

#metastatic-safety .switch-section .efficacy-link:before {
    right: 0;
    left: auto;
    transform: rotate(180deg);
}

#metastatic-safety #white-container>.container.responsivegrid:nth-of-type(2),
#metastatic-safety #white-container>.container.responsivegrid:nth-of-type(3),
#metastatic-safety .safety-main-section {
    border-bottom: 25px solid #ecf1f6;
    border-bottom: none;
}

#metastatic-safety .footnotes.pb-25 {
    padding-bottom: 47px;
    margin-top: 10px;
}

/*ISI*/
#metastatic-safety .dmmr-isi div#ISIcontent {
    scroll-margin-top: 120px;
}


#metastatic-safety #metastatic-global-footer #metastatic-safety-ref {
    display: block;
}

/* New CSS */
#metastatic-safety .footnotes__item {
    display: flex;
    position: relative;
    align-items: flex-start;
    margin: 0;
    font-size: 13px;
}

#metastatic-safety .footnotes__symbol {
    left: -1.3rem;
    width: 1.2rem;
    font-family: "Ubuntu", sans-serif;
    font-size: 64%;
    font-feature-settings: "sups" on;
    white-space: nowrap;
    line-height: normal;
    position: absolute;
    text-align: right;
    top: 0;
}
#metastatic-safety .footnotes__symbol.footnote__symbol--ast {
    font-size: 90%;
    top: 0;
}

#metastatic-safety .footnotes__text {
    color: #555;
    font-family: Ubuntu;
    font-size: 13px;
    font-style: normal;
    font-weight: 400;
    line-height: 18px;
    letter-spacing: normal;
    margin: 0 0 10px;
}

#metastatic-safety .footnotes {
    margin-bottom: 20px;
}

#metastatic-safety .key-table1 .table-block tr:nth-child(4) td:first-child,
#metastatic-safety .key-table1 .table-block tr:nth-child(6) td:first-child,
#metastatic-safety .key-table1 .table-block tr:nth-child(7) td:first-child,
#metastatic-safety .key-table1 .table-block tr:nth-child(8) td:first-child,
#metastatic-safety .key-table1 .table-block tr:nth-child(9) td:first-child,
#metastatic-safety .key-table1 .table-block tr:nth-child(10) td:first-child,
#metastatic-safety .key-table1 .table-block tr:nth-child(12) td:first-child,
#metastatic-safety .key-table1 .table-block tr:nth-child(14) td:first-child,
#metastatic-safety .key-table1 .table-block tr:nth-child(15) td:first-child,
#metastatic-safety .key-table1 .table-block tr:nth-child(16) td:first-child,
#metastatic-safety .key-table1 .table-block tr:nth-child(18) td:first-child,
#metastatic-safety .key-table1 .table-block tr:nth-child(19) td:first-child,
#metastatic-safety .key-table1 .table-block tr:nth-child(20) td:first-child,
#metastatic-safety .key-table1 .table-block tr:nth-child(22) td:first-child,
#metastatic-safety .key-table1 .table-block tr:nth-child(24) td:first-child,
#metastatic-safety .key-table1 .table-block tr:nth-child(26) td:first-child,
#metastatic-safety .key-table1 .table-block tr:nth-child(27) td:first-child,
#metastatic-safety .key-table1 .table-block tr:nth-child(29) td:first-child {
    text-indent: 25px
}

#metastatic-safety .box-image .data-compare .data-num sup {
    top: -20px;
    font-size: 60%;
}

#metastatic-safety .key-table .table-block table tbody tr>td:nth-child(n + 2):nth-child(-n + 5) {
    width: 128px;
}

#metastatic-safety .key-table1 .table-block th {
    letter-spacing: 0.038px;
    font-weight: 400;
}

#metastatic-safety #main-container #title-3ea3cdc6c9 h2 {
    padding: 10px 0;
    margin-bottom: 10px;
}

#metastatic-safety .key-table2 .table-block2 .teal-cell {
    width: 195px;
}

#metastatic-safety .key-table2 .table-block2 td:first-child {
    /*width: 240px;*/
}

#metastatic-safety .key-table2 .table-block2 td {
    padding: 7px 10px;
}

#metastatic-safety #main-container #title-ef10ba71e8 h2 {
    margin-bottom: 10px;
    padding: 10px 0;
    margin-top: 40px;
}

#metastatic-safety .key-table3 .table-block3 td:first-child {
    max-width: 262px;
}

#metastatic-safety .key-table3 .table-block3 tr:first-child td:first-child {
    border-top: none;
}

#metastatic-safety .key-table3 .table-block3 tr th:first-child {
    border-bottom: none;
}

#metastatic-safety .key-table3 .table-block3 td {
    font-size: 14px;
    font-family: 'Ubuntu';
    /* color: #003865; */
    padding: 7px 10px;
}

#metastatic-safety .key-table3 .table-block3 table tbody tr>th:nth-child(n + 2):nth-child(-n + 5) {
    width: 100px;
}

#metastatic-safety .key-table3 .table-block3 .f-teal,
#metastatic-safety .key-table3 .table-block3 th {
    font-size: 14px;
    line-height: normal;
    font-style: normal;
    font-family: 'Ubuntu';
}

#metastatic-safety .key-table3 .table-block3 tr:nth-child(2) td:first-child,
#metastatic-safety .key-table3 .table-block3 tr:nth-child(3) td:first-child,
#metastatic-safety .key-table3 .table-block3 tr:nth-child(20) td:first-child {
    color: #003865;
}

#metastatic-safety .key-table3 .table-block3 tr:nth-child(4) td:first-child,
#metastatic-safety .key-table3 .table-block3 tr:nth-child(5) td:first-child,
#metastatic-safety .key-table3 .table-block3 tr:nth-child(6) td:first-child,
#metastatic-safety .key-table3 .table-block3 tr:nth-child(7) td:first-child,
#metastatic-safety .key-table3 .table-block3 tr:nth-child(8) td:first-child,
#metastatic-safety .key-table3 .table-block3 tr:nth-child(9) td:first-child,
#metastatic-safety .key-table3 .table-block3 tr:nth-child(10) td:first-child,
#metastatic-safety .key-table3 .table-block3 tr:nth-child(11) td:first-child,
#metastatic-safety .key-table3 .table-block3 tr:nth-child(12) td:first-child,
#metastatic-safety .key-table3 .table-block3 tr:nth-child(13) td:first-child,
#metastatic-safety .key-table3 .table-block3 tr:nth-child(14) td:first-child,
#metastatic-safety .key-table3 .table-block3 tr:nth-child(15) td:first-child,
#metastatic-safety .key-table3 .table-block3 tr:nth-child(16) td:first-child,
#metastatic-safety .key-table3 .table-block3 tr:nth-child(17) td:first-child,
#metastatic-safety .key-table3 .table-block3 tr:nth-child(18) td:first-child,
#metastatic-safety .key-table3 .table-block3 tr:nth-child(19) td:first-child,
#metastatic-safety .key-table3 .table-block3 tr:nth-child(21) td:first-child,
#metastatic-safety .key-table3 .table-block3 tr:nth-child(22) td:first-child,
#metastatic-safety .key-table3 .table-block3 tr:nth-child(23) td:first-child,
#metastatic-safety .key-table3 .table-block3 tr:nth-child(24) td:first-child,
#metastatic-safety .key-table3 .table-block3 tr:nth-child(25) td:first-child {
    text-indent: 25px
}

#metastatic-safety #metastatic-global-header #main-nav nav.cmp-navigation ul.cmp-navigation__group li.cmp-navigation__item--level-0:nth-child(4) ul.cmp-navigation__dropdownmenu li a.sub-active-link,
#metastatic-safety #metastatic-global-header #main-nav nav.cmp-navigation ul.cmp-navigation__group li.cmp-navigation__item--level-0:nth-child(4) ul.cmp-navigation__dropdownmenu li:hover a.sub-active-link {
    font-weight: 700;
    font-family: "Roboto Condensed";
    border-bottom: none;
    background: url(/content/dam/intelligentcontent/brands/imfinzi-hcp/us/en/nsclc/metatastic/images/icons/white-arrow.png) no-repeat center;
    background-position-y: 31px;
}

#metastatic-safety .box-image.new-key-table {
    height: 248px;
}

#metastatic-safety .box-image.new-key-table {
    height: 248px;
}

#metastatic-safety .box-image.key-table1 {
    padding-bottom: 33px;
    margin-bottom: 28px;
}

#metastatic-safety .nospacing .footnotes__text {
    margin-bottom: 0;
}

#metastatic-safety .footnotes__item.footnotes__item--def-block {
    margin-top: 7px;
}
#metastatic-safety #wrapper-container-3 .footnotes__item.footnotes__item--def-block{
    margin-top:0;
}

#metastatic-safety .key-table1 .table-block sup {
    font-family: sans-serif;
    font-size: 50%;
    top: -0.6em;
}

#metastatic-safety .key-table2 .table-block2 {
    margin: 20px 0 5px;
}

#metastatic-safety .key-table2 .table-block2 td {
    font-size: 19.005px;
    /* line-height: 20.064px; */
}

#metastatic-safety .box-image.key-table2 {
    padding-bottom: 33px;
    margin-bottom: 30px;
}

#metastatic-safety .key-table3 .table-block3 {
    margin: 45px 0 20px;
}

#metastatic-safety .footnote-section.last-footernotes .footnotes__item.footnotes__item--def-block .footnotes__text {
    margin-bottom: 0;
}

#metastatic-safety .footnote-section.last-footernotes .footnotes {
    margin-bottom: 17px;
}

#metastatic-safety .key-table3 .table-block3 .teal-cell {
    background: rgba(229, 238, 248, 0.6);
}
#metastatic-safety #main-container {
    padding-bottom: 81px;
}
@media screen and (max-width: 991px) {

    #metastatic-safety #wrapper-container-1 .content-container,
    #metastatic-safety #wrapper-container-2 .content-container,
    #metastatic-safety #wrapper-container-3 .content-container {
        padding: 0 15px;
    }

    #metastatic-safety h1 {
        font-size: 26px;
        line-height: normal;
        /* margin: 0 15px; */
        padding: 30px 15px 15px;
        letter-spacing: -0.52px;
        padding-bottom: 24px;
    }

    #metastatic-safety .section-heading .section-head {
        padding-top: 3px;
        padding-left: 15px;
        padding-right: 15px;
    }

    #metastatic-safety .section-heading .section-head .titlemob {
        display: inline-block;
        margin-top: -3px;
        font-size: 13px;
        /* line-height: 14px; */
        padding: 9.5px 17.3px;
    }

    /* #metastatic-safety #main-container h2 {
        font-size: 21px;
        line-height: 25px;
        letter-spacing: -0.84px;
        padding: 0;
    } */
    #metastatic-safety p.box-heading:before {
        width: 42px;
        height: 25px;
        background-size: 100%;
        left: -36px;
        top: -5px;
    }

    #metastatic-safety .box-image,
    #metastatic-safety .box-image.key-table {
        /* margin: 30px 10px; */
        margin-top: 34px;
        height: auto;
        margin-bottom: 19px;
    }

    #metastatic-safety p.box-heading {
        padding: 0px 10px 10px 15px;
        width: auto;
        margin-top: -28px;
        letter-spacing: 0;
    }

    #metastatic-safety .box-image.key-table p.box-heading {
        padding: 0 6px 0 4px;
        margin-top: -28px;
        font-size: 16px;
        right: 0;
        margin-left: 0;
        margin-right: 0;
        max-width: 280px;
    }

    #metastatic-safety .box-image.key-table.key-table1 .sf-ar-1 {
        margin: 20px -15px 5px;
        margin-top: 40px;
        padding-left: 21px;
    }

    #metastatic-safety .box-image.key-table.key-table1 p.box-heading.s-line {
        /* padding-right: 15px; */
    }

    #metastatic-safety .box-image.key-table .box-heading br.m-none {
        /* display: none; */
    }

    #metastatic-safety .box-image .data-compare {
        margin: 10px auto 0;
        flex-direction: column;
        margin: 0 auto;
        padding: 40px 0 0;
        gap: 20px;
    }

    #metastatic-safety .box-image .data-compare .data-num {
        /* font-size: 50px; */
        /* line-height: 57px; */
        /* letter-spacing: -1.5px; */
        /* margin-bottom: 0; */
    }

    #metastatic-safety .box-image .data-compare p {
        font-size: 16px;
        line-height: normal;
    }

    #metastatic-safety .box-image .data-compare .data-num sup {
        top: -10px;
    }

    #metastatic-safety p.footnotes {
        font-size: 13px;
        line-height: 18px;
        color: #4A4A4A;
        font-family: 'Ubuntu';
        margin-bottom: 5px;
        position: relative;
        font-weight: 400;
        letter-spacing: 0.07px;
        /* margin-bottom: 25px; */
    }

    #metastatic-safety p.footnotes:nth-child(8),
    #metastatic-safety p.footnotes:nth-child(9),
    #metastatic-safety p.footnotes:nth-child(10) {
        margin-left: 0;
        text-indent: -4px;
    }

    #metastatic-safety .single-footnote {
        margin-left: -5px;
        font-family: 'Ubuntu', sans-serif;
        top: -0.3em;
    }

    #metastatic-safety p.footnotes sup {
        left: -1px;
        top: -.5em;
        font-size: 64%;
    }

    #metastatic-safety #wrapper-container-1 .content-container .cmp-container div:nth-child(4) .cmp-title__text.cmp-title__text--h2 {
        margin-top: 33px;
    }

    #metastatic-safety .key-table p.box-heading:before {
        top: -5px;
    }

    #metastatic-safety .footnotes.lp-01 {
        letter-spacing: 0.2px !important;
    }

    #metastatic-safety p.footnotes.footnote1.ftnote .single-footnote sup {
        top: -0.7em;
    }

    #metastatic-safety ul.patients-characteristics li {
        list-style-type: none;
        width: 47%;
        text-align: center;
    }

    #metastatic-safety .c100.center {
        scale: 0.94;
    }

    #metastatic-safety .sub-heading .sub-title {
        margin-top: 27px;
        margin-bottom: -15px;
        color: #003865;
        font-weight: 500;
        font-size: 16px;
        line-height: 18px;
        padding-left: 0px;
    }

    #metastatic-safety .box-top-content .reduction-text {
        font-size: 22px;
        line-height: 13px;
        margin: 0 auto;
        width: 100%;
    }

    #metastatic-safety .box-top-content .reduction-text .percentage-number {
        position: relative;
        left: 0px;
        font-size: 30px;
        font-weight: 900;
        line-height: 22px;
        letter-spacing: -0.9px;
    }

    #metastatic-safety .box-top-content .reduction-text .big-txt {
        font-size: 19px;
        line-height: 22px;
    }

    #metastatic-safety .box-top-content .reduction-text .blu-txt {
        font-weight: normal;
        font-size: 14px;
        line-height: 14px;
    }

    #metastatic-safety .box-top-content .box-wrap {
        max-width: 270px;
        margin: 14px auto 15px;
    }

    #metastatic-safety .box-top-content .box-wrap .box-txt {
        font-size: 15px;
        line-height: 14px;
        text-align: center;
        margin: 0 0 10px;
    }

    #metastatic-safety .box-top-content .box-wrap .box-txt.white-txt {
        width: 20px;
        height: 20px;
        font-size: 9px;
        line-height: 9px;
    }

    #metastatic-safety .box-top-content hr {
        margin: 5px 0 0;
        margin-top: 0;
        margin-bottom: 0;
    }

    #metastatic-safety .callout-wrap {
        flex-direction: column;
        padding: 40px 20px 14px 20px;
        border: 1px solid #003262;
        margin: 50px auto 20px;
        position: relative;
    }

    #metastatic-safety .callout-wrap .callout-head {
        font-size: 21px;
        line-height: 24px;
    }

    #metastatic-safety .callout-wrap .callout-copy p {
        margin-bottom: 5px;
        letter-spacing: -0.18px;
    }

    #metastatic-safety .callout-wrap img {
        width: 62px;
        height: 62px;
        margin-right: 0;
        position: absolute;
        top: -31px;
    }

    #metastatic-safety ul.patients-characteristics {
        flex-wrap: wrap;
        margin: 15px 0 20px;
        width: 93%;
        gap: 19px;
    }

    #metastatic-safety .callout-wrap .callout-txt {
        font-size: 15px;
    }

    #metastatic-safety .arrow-list {
        padding-right: 0px;
        margin-bottom: 20px;
    }

    #metastatic-safety .arrow-list li {
        font-size: 16px;
        line-height: 20px;
    }

    #metastatic-safety p.footnotes.ml-2 {
        margin-left: 0;
    }

    #metastatic-safety #wrapper-container-2 p.footnotes.ml-2 {
        margin-left: -16px;
        padding-right: 10px;
    }

    #metastatic-safety .arrow-list li.pr-20,
    #metastatic-safety .arrow-list li.pr-10 {
        padding-right: 0px;
    }

    #metastatic-safety .callout-wrap .callout-head.pr-6 {
        padding-right: 12px;
        font-size: 21px;
        line-height: 21px;
        letter-spacing: 0.18px;
    }

    #metastatic-safety #wrapper-container-3 .callout-wrap .callout-txt {
        font-size: 16px;
    }

    #metastatic-safety .callout-wrap .callout-copy p.callout-head.ls-21 {
        letter-spacing: 0.21px;
    }

    #metastatic-safety .key-table .table-block.sf-ar-1 th {
        /* font-size: 11px; */
        /* line-height: 13px; */
    }

    #metastatic-safety .key-table1 .table-block td,
    #metastatic-safety .key-table1 .table-block th,
    #metastatic-safety .key-table2 .table-block2 td,
    #metastatic-safety .key-table2 .table-block2 th,
    #metastatic-safety .key-table3 .table-block3 td,
    #metastatic-safety .key-table3 .table-block3 th {
        /* font-size: 10px; */
        /* line-height: 11px; */
        /* padding: 7px 10px; */
    }

    #metastatic-safety .key-table2 .table-block2 th,
    #metastatic-safety .key-table3 .table-block3 th {
        font-size: 14px;
        line-height: 16px;
    }

    #metastatic-safety .key-table1 .table-block td:first-child,
    #metastatic-safety .key-table2 .table-block2 td:first-child,
    #metastatic-safety .key-table3 .table-block3 td:first-child {
        max-width: 300px;
    }

    #metastatic-safety #white-container>.container.responsivegrid:nth-of-type(2),
    #metastatic-safety #white-container>.container.responsivegrid:nth-of-type(3),
    #metastatic-safety .safety-main-section {
        border-bottom: none;
    }

    #metastatic-safety .box-image.key-table.key-table3 p.box-heading {
        padding-right: 35px;
    }

    #metastatic-safety tr:not(.span-row) td:first-child::after {
        /* content: ''; */
        width: 1px;
        position: absolute;
        height: 100%;
        background: #b5cef2;
        top: 0;
        right: -1px;
        box-shadow: 0px 3px 6px #00000067;
    }



    /*Study design*/
    #metastatic-safety .hscroll-bar,
    #metastatic-safety .hscroll-bar2,
    #metastatic-safety .hscroll-bar3 {
        max-width: 299px;
        margin-left: auto;
        margin-right: auto;
        margin-top: 30px;
        border: 1px solid #808184;
        overflow: auto;
        white-space: nowrap;
        transform: rotate(180deg);
        margin-bottom: 10px;
    }

    #metastatic-safety .hscroll-bar .hscroll-thumb,
    #metastatic-safety .hscroll-bar2 .hscroll-thumb2,
    #metastatic-safety .hscroll-bar3 .hscroll-thumb3 {
        background: #ffffff;
        height: 11px;
        position: relative;
    }

    #metastatic-safety .hscroll-bar .hscroll-thumb span,
    #metastatic-safety .hscroll-bar2 .hscroll-thumb2 span,
    #metastatic-safety .hscroll-bar3 .hscroll-thumb3 span {
        position: absolute;
        height: 11px;
        background: #A5A9A5;
    }

    #metastatic-safety .table-block,
    #metastatic-safety .table-block2,
    #metastatic-safety .table-block3 {
        overflow: scroll;
    }

    #metastatic-safety .hr-scroll-txt p {
        font-weight: 700;
        font-size: 14px;
        line-height: 16px;
        letter-spacing: 0.03px;
        position: relative;
        color: #808184;
        margin: 0 0 10px;
        text-align: center;
    }

    #metastatic-safety .hr-scroll-txt p:after {
        padding-left: 3px;
        padding-top: 1px;
        /* content: '\f054'; */
        font-family: 'icomoon';
        font-weight: 100;
        font-size: 13px;
        position: absolute;
        -webkit-text-stroke: 1px #fff;
    }

    #metastatic-safety td:first-child,
    #metastatic-safety th:first-child {
        /* position: sticky; */
        /* left: 0; */
        /* background: #ffffff; */
        /* z-index: 1; */
    }

    #metastatic-safety .tbl-adverse-reactions .span-row td:nth-child(1) {
        width: 204px;
        max-width: 204px;
        display: block;
        padding: 7px 10px;
    }

    #metastatic-safety .ds-btc.table-block th {
        white-space: nowrap;
        font-size: 13px;
        line-height: 15px;
    }

    #metastatic-safety .ds-btc.table-block td {
        white-space: nowrap;
        font-size: 13px;
        line-height: 15px;
        padding: 7px 32px;
    }

    #metastatic-safety .ds-btc.table-block2 th,
    #metastatic-safety .ds-btc.table-block2 td {
        white-space: nowrap;
        font-size: 12px;
        line-height: 13px;
        padding-right: 10px;
        padding-left: 10px;
    }

    #metastatic-safety .tbl-adverse-reactions .span-row td:nth-child(2),
    #metastatic-safety .tbl-adverse-reactions .span-row td:nth-child(3) {
        padding: 7px 20px;
    }

    #metastatic-safety .table-block::-webkit-scrollbar,
    #metastatic-safety .hscroll-bar::-webkit-scrollbar,
    #metastatic-safety .table-block2::-webkit-scrollbar,
    #metastatic-safety .hscroll-bar2::-webkit-scrollbar,
    #metastatic-safety .table-block3::-webkit-scrollbar,
    #metastatic-safety .hscroll-bar3::-webkit-scrollbar {
        display: none;
    }

    #metastatic-safety .arrow-callout {
        padding: 18px 8px 18px 30px;
        margin: 0px 0 25px auto;
        margin-top: 15px;
    }

    #metastatic-safety .arrow-callout p {
        font-size: 16px;
        line-height: 18px;
    }

    #metastatic-safety .arrow-callout:before {
        width: 42px;
        height: 25px;
    }

    #metastatic-safety .box-top-content .box-wrap .box-txt .fw-light {
        font-weight: 400;
        font-size: 10px;
        line-height: 14px;
    }

    #metastatic-safety .box-image.key-table.key-table2 .box-heading {
        padding: 0px 10px 10px 15px;
        padding-right: 0;
        letter-spacing: -0.6px;
        max-width: 100%;
        width: 272px;
    }

    #metastatic-safety .patients-permanently-discontinued {
        padding: 10px 10px 10px 17px;
    }

    #metastatic-safety .patients-permanently-discontinued h2 {
        margin: 0 0 10px;
    }

    #metastatic-safety .tbl-adverse-reactions td.span-cell.pl-5.tb-3,
    #metastatic-safety .laboratory-abnormalities td.span-cell.pl-5.tb-3 {
        padding-top: 10px;
        padding-bottom: 10px;
    }

    #metastatic-safety .arrow-list li:before {
        /* content: ''; */
        /* background: url(/content/dam/intelligentcontent/brands/imfinzi-hcp/us/en/nsclc/metatastic/safety/images/list-arrow.svg) no-repeat; */
        /* position: absolute; */
        /* width: 23px; */
        /* height: 13px; */
        /* top: 3px; */
        /* left: -25px; */
        /* background-size: 23px 13px; */
    }

    #metastatic-safety .ds-btc.table-block2.laboratory-abnormalities tr:nth-child(7) td {
        height: 23px !important;
    }

    #metastatic-safety .ds-btc.table-block2.laboratory-abnormalities tr:nth-child(8) td {
        white-space: normal;
    }

    #metastatic-safety .laboratory-abnormalities .border-r-b-none.bb-none th {
        height: 35px;
    }

    #metastatic-safety .laboratory-abnormalities .border-r-b-none th {
        height: 35.5px;
    }

    #metastatic-safety .ds-btc.table-block2.laboratory-abnormalities td {
        height: auto;
        padding-top: 4.5px;
        padding-bottom: 4.5px;
    }

    #metastatic-safety .ds-btc.table-block2.laboratory-abnormalities th.clr-blue.h34 {
        padding-right: 50px;
    }


    /*Hot Link*/
    /* #metastatic-safety .safety-page-content {
        margin: 0 15px;
    } */

    #metastatic-safety .switch-section {
        margin-top: 25px;
        margin-bottom: 43px;
        margin: 0 auto;
        width: 86%;
        margin-top: 14px;
        padding-bottom: 10px;
    }

    #metastatic-safety .switch-section a {
        font-size: 16px;
        line-height: 17px;
    }

    #metastatic-safety .switch-section a.efficacy-link {
        padding: 30px 0 30px 50px;
    }

    #metastatic-safety .switch-section a.dosing-link {
        padding: 30px 50px 30px 0px;
    }

    /*ISI*/
    #metastatic-safety .dmmr-isi {
        margin-top: 10px;
    }

    #metastatic-safety .sticky-isi #sticky-isi .see-indication-container.active .see-full-container {
        height: calc(100vh - 226px);
    }

    #metastatic-safety .sticky-isi #sticky-isi .see-full-container .page-content p {
        padding: 0 23px 9px 10px;
        letter-spacing: -0.3px;
    }

    #metastatic-safety .section-isi .left-isi h2 {
        font-size: 20px;
    }

    /* New */
    #metastatic-safety #main-container h2 {
        margin: 24px 0 28px;
        padding: 0;
    }

    #metastatic-safety .box-image .data-compare .data-ver-line {
        height: 1px;
        width: 114px;
        bottom: 0;
    }

    #metastatic-safety .key-table1 .table-block tr:nth-child(4) td:first-child,
    #metastatic-safety .key-table1 .table-block tr:nth-child(6) td:first-child,
    #metastatic-safety .key-table1 .table-block tr:nth-child(7) td:first-child,
    #metastatic-safety .key-table1 .table-block tr:nth-child(8) td:first-child,
    #metastatic-safety .key-table1 .table-block tr:nth-child(9) td:first-child,
    #metastatic-safety .key-table1 .table-block tr:nth-child(10) td:first-child,
    #metastatic-safety .key-table1 .table-block tr:nth-child(12) td:first-child,
    #metastatic-safety .key-table1 .table-block tr:nth-child(14) td:first-child,
    #metastatic-safety .key-table1 .table-block tr:nth-child(15) td:first-child,
    #metastatic-safety .key-table1 .table-block tr:nth-child(16) td:first-child,
    #metastatic-safety .key-table1 .table-block tr:nth-child(18) td:first-child,
    #metastatic-safety .key-table1 .table-block tr:nth-child(19) td:first-child,
    #metastatic-safety .key-table1 .table-block tr:nth-child(20) td:first-child,
    #metastatic-safety .key-table1 .table-block tr:nth-child(22) td:first-child,
    #metastatic-safety .key-table1 .table-block tr:nth-child(24) td:first-child,
    #metastatic-safety .key-table1 .table-block tr:nth-child(26) td:first-child,
    #metastatic-safety .key-table1 .table-block tr:nth-child(27) td:first-child,
    #metastatic-safety .key-table1 .table-block tr:nth-child(29) td:first-child {
        text-indent: 20px;
    }

    #metastatic-safety .footnotes__text {
        margin-bottom: 6px;
        line-height: normal;
    }

    #metastatic-safety #wrapper-container-2 .section-heading .section-head {
        max-width: 205px;
        margin-left: 0;
        padding-top: 0;
    }

    #metastatic-safety #main-container #title-3ea3cdc6c9 h2 {
        margin-top: 13px;
        padding-top: 27px;
        margin-bottom: 14px;
        padding-bottom: 0;
    }

    #metastatic-safety .footnotes.pb-25 {
        padding-bottom: 25px;
    }

    #metastatic-safety .key-table3 .table-block3 tr:nth-child(4) td:first-child,
    #metastatic-safety .key-table3 .table-block3 tr:nth-child(5) td:first-child,
    #metastatic-safety .key-table3 .table-block3 tr:nth-child(6) td:first-child,
    #metastatic-safety .key-table3 .table-block3 tr:nth-child(7) td:first-child,
    #metastatic-safety .key-table3 .table-block3 tr:nth-child(8) td:first-child,
    #metastatic-safety .key-table3 .table-block3 tr:nth-child(9) td:first-child,
    #metastatic-safety .key-table3 .table-block3 tr:nth-child(10) td:first-child,
    #metastatic-safety .key-table3 .table-block3 tr:nth-child(11) td:first-child,
    #metastatic-safety .key-table3 .table-block3 tr:nth-child(12) td:first-child,
    #metastatic-safety .key-table3 .table-block3 tr:nth-child(13) td:first-child,
    #metastatic-safety .key-table3 .table-block3 tr:nth-child(14) td:first-child,
    #metastatic-safety .key-table3 .table-block3 tr:nth-child(15) td:first-child,
    #metastatic-safety .key-table3 .table-block3 tr:nth-child(16) td:first-child,
    #metastatic-safety .key-table3 .table-block3 tr:nth-child(17) td:first-child,
    #metastatic-safety .key-table3 .table-block3 tr:nth-child(18) td:first-child,
    #metastatic-safety .key-table3 .table-block3 tr:nth-child(19) td:first-child,
    #metastatic-safety .key-table3 .table-block3 tr:nth-child(21) td:first-child,
    #metastatic-safety .key-table3 .table-block3 tr:nth-child(22) td:first-child,
    #metastatic-safety .key-table3 .table-block3 tr:nth-child(23) td:first-child,
    #metastatic-safety .key-table3 .table-block3 tr:nth-child(24) td:first-child,
    #metastatic-safety .key-table3 .table-block3 tr:nth-child(25) td:first-child {
        text-indent: 20px;
    }
    #metastatic-safety #main-container {
    padding-bottom: 0px;
}
}