/*metastatic-efficacy*/
/*Header*/
#metastatic-efficacy #main-nav nav.cmp-navigation ul.cmp-navigation__group li.cmp-navigation__item--level-0:nth-child(3) ul.cmp-navigation__dropdownmenu li a.sub-active-link, 
#metastatic-efficacy #main-nav nav.cmp-navigation ul.cmp-navigation__group li.cmp-navigation__item--level-0:nth-child(3) ul.cmp-navigation__dropdownmenu li:hover a.sub-active-link {
    font-weight: 700;
    font-family: "Roboto Condensed";
    border-bottom: none;
    background: url(/content/dam/intelligentcontent/brands/imfinzi-hcp/us/en/hcc/efficacy/desktop/white-arrow.png) no-repeat bottom center;
}
#metastatic-efficacy #main-container {
    margin-top: 83px;
    padding: 0;
    width: 100%;
    background: url(/content/dam/intelligentcontent/brands/imfinzi-hcp/us/en/dmmr-endometrial-cancer/images/desktop/new-bg-design.png) no-repeat #ecf1f6;
    background-position-y: 0px;
    background-size: 100%;
    font-family: 'Ubuntu';
}
#metastatic-efficacy #title-bar {
    padding: 78px 0 55px;
}
#metastatic-efficacy #title-bar h1 {
    font-size: 38px;
    line-height: normal;
    color: #003865;
    max-width: 850px;
    margin: 0 auto;
    font-weight: 700;
}
#metastatic-efficacy #title-bar .sub-head p {
    font-size: 24px;
    font-style: normal;
    font-weight: 500;
    line-height: normal;
    margin-top: 38px;
    color: #003865;
}
/* #metastatic-efficacy .main-callout {
    margin: 28px auto -2px;
    border: 0.5px solid #03315D;
    max-width: 680px;
    position: relative;
    margin-bottom: 28px;
}
#metastatic-efficacy .main-callout p {
    padding: 15.5px 50px;
    font-size: 21px;
    line-height: 25px;
    letter-spacing: 0.21px;
    font-weight: 500;
    color: #00AB9C;
}
#metastatic-efficacy .main-callout:before {
    content: '';
    background: url(/content/dam/intelligentcontent/brands/imfinzi-hcp/us/en/dmmr-endometrial-cancer/images/mobile/callout-arrow.svg) no-repeat;
    position: absolute;
    width: 61px;
    height: 36px;
    top: 7px;
    left: -22px;
} */

#metastatic-efficacy .sub-heading .sub-title {
    margin-top: 48px;
    margin-bottom: -20px;
    color: #003865;
    font-weight: 500;
    font-size: 16px;
    line-height: 22px;
}
#metastatic-efficacy .subhead {
    font-size: 20px;
    line-height: 24px;
    font-weight: 400;
    color: #003865;
    margin: 0 0 26px;
}
#metastatic-efficacy .list-text-color-blue {
    color: #555454;
    font-size: 16px;
    line-height: normal;
    font-weight: 400;
    margin-bottom: 27px;
}
#metastatic-efficacy .nccn-sec {
    color: #003865;
    display: flex;
    justify-content: space-between;
    align-items: center;
    width: 100%;
    padding: 10px;
    border-top: 2.12px solid #003865;
    border-bottom: 2.12px solid #003865;
    margin: 20px auto 37px;
}
#metastatic-efficacy .nccn-sec .nccn-heading p {
    padding-right: 15px;
    border-right: 2.20px solid #003865;
    font-weight: 700;
    font-size: 48px;
    line-height: 21px;
    padding-top: 10px;
    margin: 0 0 10px;
    margin-bottom: 0;
}
#metastatic-efficacy .nccn-heading p span {
    font-size: 21px;
}
#metastatic-efficacy .nccn-content {
    padding-left: 12.5px;
}
#metastatic-efficacy .nccn-content p {
    font-size: 14px;
    line-height: normal;
    font-weight: 400;
    margin: 0 0 10px;
    margin-bottom: 0;
    color: #003865;
}
#metastatic-efficacy .nccn-content p b {
    line-height: normal;
}
#metastatic-efficacy .sample-text {
    font-size: 16px;
    line-height: normal;
    color: #555454;
    font-weight: 400;
    margin: 0 0 27px;
}
#metastatic-efficacy .sample-text b {
    font-weight: 700;
}
#metastatic-efficacy .sample-text .custom-bracket {
    font-size: 17px;
}
#metastatic-efficacy .hr-footnote {
    text-align: center;
    font-size: 16px;
    line-height: 18px;
    font-weight: 400;
    color: #555454;
    margin: 10px auto;
}


#metastatic-efficacy .anchoring-section .page-content {
    max-width: 680px;
    padding-bottom: 0;
    margin: 0 auto;
}
#metastatic-efficacy .anchoring-section .pos-eff-links {
    width: 100%;
    display: inline-flex;
    justify-content: center;
    align-items: center;
    margin: 20px auto;
}
#metastatic-efficacy .anchoring-section .callout-link {
    border: 0.5px solid #03315D;
    max-width: 680px;
    position: relative;
}
#metastatic-efficacy .anchoring-section .callout-link:before {
    content: '';
    background: url(/content/dam/intelligentcontent/brands/imfinzi-hcp/us/en/dmmr-endometrial-cancer/images/mobile/callout-arrow.svg) no-repeat;
    position: absolute;
    width: 61px;
    height: 36px;
    left: -22px;
    top: auto;
}
#metastatic-efficacy .anchoring-section .callout-link.pos-eff-links p {
    font-size: 18px;
    line-height: 25px;
    letter-spacing: 0;
    padding: 28px 10px 28px 25px;
    font-weight: 500;
    color: #00AB9C;
    margin: 0 0 10px;
    margin-bottom: 0;
}
#metastatic-efficacy .anchoring-section .callout-link.pos-eff-links .ef-anchor-sec a {
    font-size: 14px;
    line-height: 16px;
    font-weight: 700;
    color: #003865;
    background: #EBF1F8;
    padding: 13.5px 19px;
}
#metastatic-efficacy .anchoring-section .callout-link.pos-eff-links .ef-anchor-sec a:after {
    content: '\f078';
    font-family: 'icomoon';
    padding-left: 5px;
    font-weight: 100;
    color: #AC182E;
}
#metastatic-efficacy .anchoring-section .callout-link.pos-eff-links .ef-anchor-sec a.anchor-up:after {
    content: '\f077';
}
#metastatic-efficacy .anchoring-section .callout-link.pos-eff-links .ef-anchor-sec a:hover,
#metastatic-efficacy .anchoring-section .callout-link.pos-eff-links .ef-anchor-sec a:hover::after{
    color: #ffffff;
    background: #00AB9C;
    text-decoration: none;
}

/*tab*/
#metastatic-efficacy ol.cmp-tabs__tablist {
    border-bottom: 1px solid #6F99D2;
    margin: 25px 0 0;
    position: relative;
}
#metastatic-efficacy ol.cmp-tabs__tablist .cmp-tabs__tab {
    box-sizing: border-box;
    border-top: 1px solid #6F99D2;
    padding: 6.5px 15px 6.5px;
    cursor: pointer;
    background: #F0F5FC;
    color: #003865;
    font-weight: 400;
    font-size: 12px;
    line-height: 13px;
}
#metastatic-efficacy ol.cmp-tabs__tablist .cmp-tabs__tab:not(:last-child)::after {
    content: '';
    border-left: 1px solid #003865;
    width: 1px;
    position: relative;
    right: -15px;
    padding: 5px 0;
}
#metastatic-efficacy ol.cmp-tabs__tablist .cmp-tabs__tab.cmp-tabs__tab--active,
#metastatic-efficacy ol.cmp-tabs__tablist .cmp-tabs__tab:hover {
    text-decoration: underline 3px solid #AC172D;
    text-underline-offset: 6.5px;
    border-bottom: 0;
    font-weight: 700;
}
#metastatic-efficacy ol.cmp-tabs__tablist .cmp-tabs__tab:first-child {
    border-top: 1px solid #6F99D2;
    border-left: 1px solid #6F99D2;
    border-top-left-radius: 10px;
}
#metastatic-efficacy ol.cmp-tabs__tablist .cmp-tabs__tab:last-child {
    border-top: 1px solid #6F99D2;
    border-right: 1px solid #6F99D2;
    border-top-right-radius: 10px;
}




#metastatic-efficacy #white-container {
    max-width: 950px;
    background: #ffffff;
    margin: 0 auto;
}
#metastatic-efficacy .content-container {
    max-width: 850px;
    margin: 0 auto;
}
#metastatic-efficacy .cmp-text {
    font-family: 'Ubuntu';
    padding: 0;
}
#metastatic-efficacy .section-heading {
    border-top: 1px solid #00618b;
}
#metastatic-efficacy .section-heading p {
    max-width: 850px;
    margin: 0 auto;
    padding-top: 11px;
}
#metastatic-efficacy .section-heading span {
    color: #ffffff;
    background: #003865;
    font-size: 15px;
    line-height: normal;
    font-weight: 700;
    padding: 11px 17.4px;
    border-bottom-left-radius: 20px;
    border-bottom-right-radius: 20px;
}
#metastatic-efficacy #main-container h2 {
    font-size: 24px;
    line-height: normal;
    color: #003865;
    font-weight: 500;
    padding: 18px 0 0px;
    margin: 18px 0px 23px 0;
}
#metastatic-efficacy #main-container #last-title-iit h2 {
    padding: 10px 0 0;
    padding-bottom: 3px;
}
#metastatic-efficacy sup {
    font-size: 75%;
    top: -.5em;
    line-height: 0;
    position: relative;
    vertical-align: baseline;
}
#metastatic-efficacy .subhead .ast-sup {
    top: -4px;
    position: relative;
}
#metastatic-efficacy #sec-1-tab-2 .cmp-title__text,
#metastatic-efficacy #sec-1-tab-3 .cmp-title__text,
#metastatic-efficacy #sec-2-tab-3 .cmp-title__text,
#metastatic-efficacy #sec-3-tab-3 .cmp-title__text,
#metastatic-efficacy #sec-4-tab-1 .cmp-title__text {
    margin-top: 25px;
}

/* #metastatic-efficacy .box-image.dor-iit-img img {
    padding-top: 10px;
} */


#metastatic-efficacy .box-image .data-compare {
    margin: 32px auto 25px;
    max-width: 500px;
    justify-content: space-between;
    display: flex;
    align-items: center;
    width: 100%;
}
#metastatic-efficacy .box-image .data-compare p {
    margin: 0 0 10px;
    text-align: center;
    font-size: 16px;
    line-height: 18px;
    font-weight: 400;
}
#metastatic-efficacy .box-image .data-compare .data-num {
    font-size: 61px;
    line-height: normal;
    font-weight: 700;
    margin-bottom: 0;
}
#metastatic-efficacy .box-image .data-compare .data-num span {
    font-size: 22px;
    line-height: 26px;
}
#metastatic-efficacy .box-image .data-compare .data-grey-txt p {
    color: #6F7175;
}
#metastatic-efficacy .box-image .data-compare .data-teal-txt p {
    color: #007A6D;
}
#metastatic-efficacy .box-image .data-compare .data-ver-line {
    background: #003865;
    width: 0.5px;
    height: 110px;
}
#metastatic-efficacy .box-image .data-compare .data-content {
    font-size: 16px;
    line-height: normal;
}
#metastatic-efficacy .box-image {
    border: 0.5px solid #003865;
    max-width: 850px;
    margin: 48px auto 21px;
    padding: 20px;
    border-radius: 32px;
}
#metastatic-efficacy .box-image.box-image--circles {
    margin-top: 20px;
}
#metastatic-efficacy .box-image.os-pd-l1-img {
    margin-bottom: 10px;
}
#metastatic-efficacy .box-image.os-stk11-img {
    margin: 40px auto 20px;
}
#metastatic-efficacy .box-image.os-keap1-img {
    margin-top: 40px;
}
#metastatic-efficacy .box-image.os-stk11-img p.box-heading.s-line {
    line-height: 18px;
}
#metastatic-efficacy .box-image.os-stk11-img img {
    padding: 12px 0 0;
    margin: 0 auto;
    margin-top: 15px;
}
#metastatic-efficacy .box-image.os-keap1-img img {
    padding: 10px 0 5px;
    margin: 0 auto;
    margin-top: 10px;
}
#metastatic-efficacy .box-image.os-kras-img {
    margin-top: 40px;
}

#metastatic-efficacy ul.arrow-list.first-list.mb-33 {
    margin-bottom: 33px;
}

/* #metastatic-efficacy .box-image.os-iit-subgroup-img,
#metastatic-efficacy .box-image.pfs-iit-img,
#metastatic-efficacy .box-image.os-kras-img,
#metastatic-efficacy .box-image.os-skt-img,
#metastatic-efficacy .box-image.pfs-iit-img {
    margin-top: 20px;
} */
#metastatic-efficacy .box-image img {
    margin: 45px auto 29px;
}
#metastatic-efficacy .box-image.os-iit-subgroup-img img {
    margin-top: 24px;
    margin-bottom: 8px;
    max-width: 819px;
}
#metastatic-efficacy .box-image.os-kras-img img,
#metastatic-efficacy .box-image.os-pd-l1-img img {
    padding-top: 12px;
    margin: 0 auto;
    margin-top: 10px;
}
#metastatic-efficacy .spacer {
    padding-bottom: 10px;
    display: block;
}
#metastatic-efficacy .box-image.pfs-iit-img .list-sec {
    margin-top: 5px;
}
#metastatic-efficacy .box-image.os-skt-img img {
    padding: 10px 0 5px;
}
#metastatic-efficacy #wrapper-container-2 #sec-2-tab-1 h2,
#metastatic-efficacy #wrapper-container-2 #sec-2-tab-2 h2,
#metastatic-efficacy #wrapper-container-3 #sec-3-tab-1 h2,
#metastatic-efficacy #wrapper-container-3 #sec-3-tab-2 h2 {
    margin-top: 40px;
}
#metastatic-efficacy #sec-3-tab-2 .box-image.pfs-iit-img {
    margin-top: 15px;
}
#metastatic-efficacy p.box-heading {
    
    line-height: normal;
    letter-spacing: 0.03px;
    color: #003865;
    font-weight: 500;
    position: relative;
    padding: 0 10px 0 6px;
    background: #ffffff;
    margin: 0 21px;
    width: fit-content;
}
#metastatic-efficacy .box-heading.box-heading-duos {
    margin-top: -30px;
    margin-bottom: 10px;
    font-weight: 500;
    font-size: 16px;
}
#metastatic-efficacy p.box-heading.s-line {
    margin-top: -30px;
    font-weight: 500;
    font-size: 18px;
}
#metastatic-efficacy .box-image.key-table sup,
#metastatic-efficacy .list-sec ul.arrow-list sup,
#metastatic-efficacy .footnote-section .footnotes sup,
#metastatic-efficacy #main-container #wrapper-container-2 h2 sup,
#metastatic-efficacy #main-container #wrapper-container-3 h2 sup {
    font-size: 75%;
    top: -.5em;
    line-height: 0;
    position: relative;
    vertical-align: baseline;    
}
#metastatic-efficacy .box-image.key-table .ast-sup {
    top: -4px;
    position: relative;
}
#metastatic-efficacy .box-image.key-table .data-num sup {
    top: -8px;
}
#metastatic-efficacy p.box-heading:before{
    content: '';
    background: url(/content/dam/intelligentcontent/brands/imfinzi-hcp/us/en/dmmr-endometrial-cancer/images/mobile/callout-arrow.svg) no-repeat;
    width: 61px;
    height: 36px;
    position: absolute;
    left: -42px;
    top: -8px;
    display: none;
}
#metastatic-efficacy .box-image.key-table.key-table1 p.box-heading {
    margin-top: -30px;
}
#metastatic-efficacy p.footnotes {
    font-size: 13px;
    line-height: normal;
    color: #4A4A4A;
    font-family: 'Ubuntu';
    margin-bottom: 5px;
    position: relative;
    font-weight: 400;
    letter-spacing: normal;
    padding-right: 1px;
}
#metastatic-efficacy p.footnotes.pb-25 {
    padding-bottom: 50px;
}
#metastatic-efficacy p.footnotes.mb-0 {
    margin-bottom: 0px;
}
#metastatic-efficacy p.footnotes .ast-footnote {
    margin-left: -7px;
}
#metastatic-efficacy .single-footnote,
#metastatic-efficacy .double-footnote {
    margin-left: -5px;
    font-family: 'Ubuntu', sans-serif;
}
#metastatic-efficacy .key-table p.box-heading:before {
    top: -8px;
}
#metastatic-efficacy table {
    border-collapse: collapse;
    border-spacing: 0;
    width: 100%;
    margin: 0 auto;
}
#metastatic-efficacy .key-table1 .table-block td:first-child,
#metastatic-efficacy .key-table2 .table-block2 td:first-child,
#metastatic-efficacy .key-table3 .table-block3 td:first-child {
    max-width: 260px;
}
#metastatic-efficacy .key-table1 .table-block tr.span-row td,
#metastatic-efficacy .key-table2 .table-block2 tr.span-row td,
#metastatic-efficacy .key-table3 .table-block3 tr.span-row td {
    border-right: none;
}
#metastatic-efficacy .key-table1 .table-block tr.span-row td:first-child,
#metastatic-efficacy .key-table2 .table-block2 tr.span-row td:first-child,
#metastatic-efficacy .key-table3 .table-block3 tr.span-row td:first-child {
    font-weight: 700;
}
#metastatic-efficacy .key-table1 .table-block .f-teal,
#metastatic-efficacy .key-table2 .table-block2 .f-teal,
#metastatic-efficacy .key-table3 .table-block3 .f-teal {
    color: #00AB9C;
}
#metastatic-efficacy .key-table1 .table-block .teal-cell,
#metastatic-efficacy .key-table2 .table-block2 .teal-cell,
#metastatic-efficacy .key-table3 .table-block3 .teal-cell {
    background: #F0F5FC;
    color: #00AB9C;
    font-weight: 700;
}
#metastatic-efficacy .key-table1 .table-block td, 
#metastatic-efficacy .key-table1 .table-block th,
#metastatic-efficacy .key-table2 .table-block2 td, 
#metastatic-efficacy .key-table2 .table-block2 th,
#metastatic-efficacy .key-table3 .table-block3 td, 
#metastatic-efficacy .key-table3 .table-block3 th {
    font-size: 14px;
    line-height: 16px;
    padding: 7px 10px;
}
#metastatic-efficacy .key-table1 .table-block,
#metastatic-efficacy .key-table2 .table-block2,
#metastatic-efficacy .key-table3 .table-block3 {
    margin: 20px auto 5px;
    max-width: 615px;
}
#metastatic-efficacy td, 
#metastatic-efficacy th {
    text-align: center;
    font-weight: 400;
    font-size: 14px;
    line-height: 14px;
    color: #4e5055;
    border-right: 1px solid #707070;
    border-bottom: 1px solid #707070;
    padding: 10px 0;
    white-space: nowrap;
}
#metastatic-efficacy th {
    font-weight: 700;
    border-top: none;
    padding: 10px 0;
}
#metastatic-efficacy td:first-child {
    text-align: left;
    border-left: none
}
#metastatic-efficacy .box-image.key-table.key-table2 th:first-child {
    text-align: left;
    border-left: none;
    border-bottom: none;
}
#metastatic-efficacy td:last-child, 
#metastatic-efficacy th:last-child {
    border-right: none
}
#metastatic-efficacy table tr:last-child td {
    border-bottom: none;
}
#metastatic-efficacy .footnotes.footnote-last {
    margin-bottom: 50px;
    margin-top: 30px;
}
#metastatic-efficacy .box-image.key-table.key-table2 .box-heading {
    max-width: 515px;
    width: 515px;
    margin-top: -30px;
}

#metastatic-efficacy .arrow-list {
    list-style-type: none;
    padding-left: 32px;
    margin-bottom: 10px;
    margin-top: 0;
}
#metastatic-efficacy .arrow-list li {
    font-size: 16px;
    line-height: 20px;
    margin-bottom: 15px;
    font-family: "Ubuntu", sans-serif;
    font-weight: 400;
    position: relative;
    color: #555555;
}
#metastatic-efficacy ul.arrow-list.first-list{
    margin-bottom: 20px;
}
#metastatic-efficacy .arrow-list li.mb-0 {
    margin-bottom: 0;
}
#metastatic-efficacy .box-image.pfs-iit-img ul.arrow-list li {
    margin-bottom: 0;
}
#metastatic-efficacy .arrow-list li:before {
    content: '';
    background: url(/content/dam/intelligentcontent/brands/imfinzi-hcp/us/en/nsclc/metatastic/efficacy/images/list-arrow.svg) no-repeat;
    position: absolute;
    width: 26px;
    height: 13px;
    top: 5px;
    left: -33px;
}
#metastatic-efficacy .arrow-list.first-list .fw-bold {
    font-weight: 700;
}

#metastatic-efficacy .box-image.box-image--circles .eyebrow {
    color: #003865;
    font-weight: 500;
    line-height: normal;
    font-size: 16px;
    margin: 0px auto -20px;
}
#metastatic-efficacy .box-image.box-image--circles .prevalence {
    display: flex;
    align-items: center;
}
#metastatic-efficacy .box-image.box-image--circles .prevalence img {
    margin: 0 auto;
}
#metastatic-efficacy .box-image.box-image--circles .prevalence .prevalence-contnet {
    margin-top: 30px;
}
#metastatic-efficacy .box-image.box-image--circles .eyebrow span {
    position: relative;
    top: -2px;
}
#metastatic-efficacy .box-image.box-image--circles .prevalence .prevalence-contnet p {
    font-family: Ubuntu;
    font-size: 16px;
    font-style: normal;
    font-weight: 400;
    line-height: normal;
    color: #003865;
    margin: 0 0 10px;
}
#metastatic-efficacy .box-image.box-image--circles .prevalence .prevalence-contnet p:first-of-type {
    margin-bottom: 24px;
}
#metastatic-efficacy .box-image.box-image--circles .prevalence .prevalence-contnet p:last-of-type {
    color: #4A4A4A;
    font-size: 13px;
    font-weight: 400;
    text-indent: -5px;
    margin-top: 16px;
}

#metastatic-efficacy .per-block {
    display: flex;
    align-items: center;
    border-radius: 23px;
    border: 1px solid #AD1F2F;
    background: #FFF;
    padding: 25px 23px;
    position: relative;
    margin-bottom: 27px;
}
#metastatic-efficacy .per-block h5 {
    width: 64px;
    height: 64px;
    background: #007A6D;
    color: #fff;
    border-radius: 50px;
    font-size: 31.5px;
    font-style: normal;
    font-weight: 700;
    line-height: normal;
    letter-spacing: -1.575px;
    position: absolute;
    display: flex;
    align-items: center;
    justify-content: center;
    gap: 2px;
    margin-top: 10px;
    margin-bottom: 10px;
}
#metastatic-efficacy .per-block h5 span {
    font-size: 18px;
}
#metastatic-efficacy #main-container .per-block h2 {
    font-size: 20px;
    font-style: normal;
    font-weight: 700;
    line-height: normal;
    color: #007A6D;
    padding: 0 50px 0 81px;
    margin: 0;
}

#metastatic-efficacy #main-container #stk11-title h2 {
    padding-top: 0;
    margin-top: 48px;
}

#metastatic-efficacy #main-container #keap1-title h2 {
    margin: 0;
    margin-top: 48px;        
    padding: 26px 0 0;
}

#metastatic-efficacy #main-container #kras-title h2 {
    margin-top: 48px;  
    padding: 10px 0 0;
}

/*Hot links*/
#metastatic-efficacy .safety-page-content {
    max-width: 850px;
    margin: 0 auto;
}
#metastatic-efficacy .switch-section {
    margin: 0px auto;
    display: flex;
    width: 80%;
    justify-content: space-between;
    position: relative;
    align-items: center;
}
#metastatic-efficacy .switch-section a {
    color: #003865;
    font-weight: 700;
    font-size: 16px;
    line-height: 20px;
    padding: 35px 50px 30px;
    font-family: 'Ubuntu';
}
#metastatic-efficacy .switch-section a:before {
    background: url(/content/dam/intelligentcontent/brands/imfinzi-hcp/us/en/biliary-tract-cancer/about-btcs/images/page-switch-icon.png) no-repeat;
    content: '';
    width: 32px;
    height: 32px;
    position: absolute;
    left: 0;
    top: 28px;
}
#metastatic-efficacy .switch-section .safety-link:before {
    right: 0;
    left: auto;
    transform: rotate(180deg);
}
#metastatic-efficacy #white-container > .container.responsivegrid:nth-of-type(6) {
    border-bottom: 43px solid #ecf1f6;
}
#metastatic-efficacy .footnotes.pb-25 {
    padding-bottom: 25px;
}

/*ISI*/
#metastatic-efficacy .dmmr-isi div#ISIcontent {
    scroll-margin-top: 120px;
}

#metastatic-efficacy #metastatic-global-footer #metastatic-efficacy-ref {
    display: block;
}
#metastatic-efficacy .dmmr-footer .reference-section{
    padding: 0 19px 0 0;
}
#metastatic-efficacy .section-isi h2 {
    margin-top: 20px;
}

@media screen and (max-width: 991px) {

    #metastatic-efficacy #title-bar {
        padding: 30px 0 20px;
        margin: 0 15px;
    }
    #metastatic-efficacy #title-bar .sub-head p {
        font-size: 20px;
        font-style: normal;
        font-weight: 500;
        line-height: normal;
        margin-top: 38px;
        color: #003865;
        letter-spacing: -0.52px;
    }
    #metastatic-efficacy #main-container h2 {
        font-size: 24px;
        line-height: normal;
        color: #003865;
        font-weight: 500;
        padding: 18px 0 0px;
        margin: 6px 0px 10px 0;
    }
    #metastatic-efficacy #main-container #stk11-title h2 {
        margin-top: 40px;
    }
    #metastatic-efficacy #main-container #last-title-iit h2 {
        margin-top: 40px;
    }
    #metastatic-efficacy .box-image .data-compare .data-ver-line {
        background: #003865;
        width: 0.5px;
        width: 110px;
        height: 0.5px;
        margin: 11px 0 6px;
    }

    #metastatic-efficacy #wrapper-container-1 .content-container,
    #metastatic-efficacy #wrapper-container-2 .content-container,
    #metastatic-efficacy #wrapper-container-3 .content-container,
    #metastatic-efficacy #wrapper-container-4 .content-container {
        margin: 0 15px;
    }
    #metastatic-efficacy .main-callout {
        margin: 10px 15px 25px 37px;
    }
    #metastatic-efficacy .main-callout p {
        padding: 15.5px 34px;
        font-size: 18px;
        line-height: 20px;
        letter-spacing: 0px;
    }
    #metastatic-efficacy .main-callout:before {
        width: 42px;
        height: 25px;
        background-size: 100%;
        left: -16px;
        top: 8px;
    }
    #metastatic-efficacy ol.cmp-tabs__tablist .cmp-tabs__tab {
        font-size: 11px;
        line-height: 12px;
        padding: 16.5px 11px 13.5px;
    }
    #metastatic-efficacy #title-bar h1 {
        font-size: 26px;
        line-height: 29px;
        letter-spacing: -0.52px;
    }
    #metastatic-efficacy .anchoring-section .pos-eff-links {
        flex-direction: column;
        padding-bottom: 30px;
        margin: 20px 5px 30px;
    }
    #metastatic-efficacy .anchoring-section .callout-link.pos-eff-links p {
        padding: 15px 0px 20px 20px;
        font-size: 16px;
        line-height: 20px;
    }
    #metastatic-efficacy .section-heading .section-head {
        padding-top: 3px;
        padding-left: 15px;
    }
    #metastatic-efficacy .anchoring-section .callout-link:before {
        width: 42px;
        height: 25px;
        background-size: 100%;
        left: -16px;
        top: 13px;
    }
    #metastatic-efficacy .anchoring-section {
        margin: 0 15px;
    }
    #metastatic-efficacy .anchoring-section.last-divider {
        margin: 0 30px;
    }
    #metastatic-efficacy .anchoring-section .callout-link.pos-eff-links .ef-anchor-sec a {
        padding: 13.5px 12px;
    }
    #metastatic-efficacy .section-heading .section-head .titlemob {
        display: inline-block;
        margin-top: -3px;
        font-size: 15px;
        line-height: normal;
        padding: 9.5px 17.3px;
    }
    #metastatic-efficacy .nccn-sec {
        /* flex-direction: column; */
        margin-bottom: 21px;
    }
    #metastatic-efficacy .nccn-sec .nccn-heading p {
        border-right: none;
        padding-right: 9px;
        padding-bottom: 12px;
    }
    #metastatic-efficacy .nccn-content {
        padding-left: 0;
    }
    #metastatic-efficacy .nccn-content p {
        padding-top: 0;
        margin-right: -23px;
        border-left: 1.5px solid #003865;
        padding-left: 9px;
    }
    #metastatic-efficacy .nccn-content p b {
        line-height: normal;
    }
    #metastatic-efficacy .sample-text {
        font-size: 16px;
        margin-bottom: 18px;
    }
    #metastatic-efficacy p.box-heading:before {
        width: 42px;
        height: 25px;
        background-size: 100%;
        left: -36px;
        top: -5px;
    }
    #metastatic-efficacy .box-image, 
    #metastatic-efficacy .box-image.key-table {
        margin: 30px 0 24px;
        padding: 20px 9px 30px;
        border: 0.75px solid #003865;
    }
    #metastatic-efficacy .box-image.os-iit-subgroup-img p.box-heading.s-line {
        font-size: 16px;
        line-height: normal;
        padding: 0 4px;
        margin-left: 15px;
        max-width: 272px;
        padding-left: 5px;
    }
    #metastatic-efficacy p.box-heading {
        padding: 0 10px 0 3px;
        font-size: 16px;
        line-height: normal;
        letter-spacing: 0;
        width: fit-content;
        margin: 0 21px;
    }
    #metastatic-efficacy .box-image.os-stk11-img p.box-heading.s-line {
        margin-left: 16px;
        padding: 0 0px 0 0px;
        padding-left: 5px;
        width: 92%;
    }
    #metastatic-efficacy .box-heading.box-heading-duos {
        margin-top: -30px;
        margin-bottom: 10px;
        font-weight: 500;
        max-width: 250px;
        padding-left: 5px;
    }
    #metastatic-efficacy .box-image.key-table p.box-heading {
        font-size: 12px;
        line-height: 15px;
        letter-spacing: 0;
        padding: 0px 0 0 15px;
        margin-top: -28px;
    }
    #metastatic-efficacy .box-image.key-table.key-table1 .sf-ar-1 {
        margin: 20px -15px 5px;
    }
    #metastatic-efficacy .box-image.key-table.key-table1 p.box-heading.s-line {
        padding-right: 15px;
    }
    #metastatic-efficacy .box-image.key-table .box-heading br.m-none {
        display: none;
    }
    #metastatic-efficacy .box-image .data-compare {
        margin: 32px auto 25px;
        max-width: 283px;
        flex-direction: column;
    }
    #metastatic-efficacy .box-image.pfs-iit-img {
        padding: 20px 9px 25px;
    }
    #metastatic-efficacy .box-image.os-stk11-img img {
        margin: 0 auto;
        max-width: 331px;
        padding-top: 20px;
        width: 100%;
    }
    #metastatic-efficacy .box-image.pfs-iit-img .box-heading.s-line {
        font-size: 16px;
        line-height: normal;
        margin-left: 20px;
        max-width: 215px;
        padding-left: 5px;
    }
    #metastatic-efficacy .box-image .data-compare .data-num {
        font-size: 61px;
        line-height: normal;
        margin-bottom: 0;
        display: flex;
        align-items: flex-end;
    }
    #metastatic-efficacy .hr-footnote {
        font-size: 16px;
        line-height: normal;
        margin: 15px auto 32px;
    }
    #metastatic-efficacy .box-image .data-compare p {
        font-size: 12px;
        line-height: 13px;
    }
    #metastatic-efficacy .box-image .data-compare .data-num sup {
        top: -10px;
    }
    #metastatic-efficacy p.footnotes {
        font-size: 13px;
        line-height: normal;
        color: #4A4A4A;
        font-family: 'Ubuntu';
        margin-bottom: 5px;
        position: relative;
        font-weight: 400;
        letter-spacing: normal;
    }
    #metastatic-efficacy p.footnotes.pb-25.mpb-42 {
        padding-bottom: 42px;
    }
    #metastatic-efficacy p.footnotes.mb-0 {
        margin-bottom: 5px;
        padding-right: 0;
    }
    #metastatic-efficacy p.footnotes:nth-child(8),
    #metastatic-efficacy p.footnotes:nth-child(9),
    #metastatic-efficacy p.footnotes:nth-child(10) {
        margin-left: 0;
        text-indent: -4px;
    }
    #metastatic-efficacy .single-footnote {
        margin-left: -5px;
        font-family: 'Ubuntu', sans-serif;
        top: -0.3em;
    }
    #metastatic-efficacy p.footnotes sup {
        left: -1px;
        top: -.5em;
        font-size: 64%;
    }
    /* #metastatic-efficacy #wrapper-container-1 .content-container .cmp-container div:nth-child(4) .cmp-title__text.cmp-title__text--h2 {
        margin-top: 33px;
    } */
    #metastatic-efficacy .key-table p.box-heading:before {
        top: -5px;
    }
    #metastatic-efficacy .footnotes.lp-01 {
        letter-spacing: 0.2px !important;
    }
    #metastatic-efficacy p.footnotes.footnote1.ftnote .single-footnote sup {
        top: -0.7em;
    }
    #metastatic-efficacy ul.patients-characteristics li {
        list-style-type: none;
        width: 47%;
        text-align: center;
    }
    #metastatic-efficacy .c100.center {
        scale: 0.94;
    }
    #metastatic-efficacy .sub-heading .sub-title {
        margin-top: 13px;
        margin-bottom: -20px;
        color: #003865;
        font-weight: 500;
        font-size: 16px;
        line-height: normal;
    }
    #metastatic-efficacy .box-top-content .reduction-text {
        font-size: 22px;
        line-height: 13px;
        margin: 0 auto;
        width: 100%;
    }
    #metastatic-efficacy .box-top-content .reduction-text .percentage-number {
        position: relative;
        left: 0px;
        font-size: 30px;
        font-weight: 900;
        line-height: 22px;
        letter-spacing: -0.9px;
    }
    #metastatic-efficacy .box-top-content .reduction-text .big-txt {
        font-size: 19px;
        line-height: 22px;
    }
    #metastatic-efficacy .box-top-content .reduction-text .blu-txt {
        font-weight: normal;
        font-size: 14px;
        line-height: 14px;
    }
    #metastatic-efficacy .box-top-content .box-wrap {
        max-width: 270px;
        margin: 14px auto 15px;
    }
    #metastatic-efficacy .box-top-content .box-wrap .box-txt {
        font-size: 15px;
        line-height: 14px;
        text-align: center;
        margin: 0 0 10px;
    }
    #metastatic-efficacy .box-top-content .box-wrap .box-txt.white-txt {
        width: 20px;
        height: 20px;
        font-size: 9px;
        line-height: 9px;
    }
    #metastatic-efficacy .box-top-content hr {
        margin: 5px 0 0;
        margin-top: 0;
        margin-bottom: 0;
    }
    #metastatic-efficacy .callout-wrap {
        flex-direction: column;
        padding: 40px 20px 14px 20px;
        border: 1px solid #003262;
        margin: 50px auto 20px;
        position: relative;
    }
    #metastatic-efficacy .callout-wrap .callout-head {
        font-size: 21px;
        line-height: 24px;
    }
    #metastatic-efficacy .callout-wrap .callout-copy p {
        margin-bottom: 5px;
        letter-spacing: -0.18px;
    }
    #metastatic-efficacy .callout-wrap img {
        width: 62px;
        height: 62px;
        margin-right: 0;
        position: absolute;
        top: -31px;
    }
    #metastatic-efficacy ul.patients-characteristics {
        flex-wrap: wrap;
        margin: 15px 0 20px;
        width: 93%;
        gap: 19px;
    }
    #metastatic-efficacy .callout-wrap .callout-txt {
        font-size: 15px;
    }
    #metastatic-efficacy .arrow-list {
        padding-right: 0px;
        margin-bottom: 20px;
    }
    #metastatic-efficacy .arrow-list li {
        font-size: 16px;
        line-height: 20px;
    }
    #metastatic-efficacy .arrow-list li.pr-1 {
        padding-right: 1px;
    }
    #metastatic-efficacy p.footnotes.ml-2 {
        margin-left: 0;
    }
    #metastatic-efficacy #wrapper-container-2 p.footnotes.ml-2 {
        margin-left: -16px;
        padding-right: 10px;
    }
    #metastatic-efficacy .arrow-list li.pr-20, #metastatic-efficacy .arrow-list li.pr-10 {
        padding-right: 0px;
    }
    #metastatic-efficacy .callout-wrap .callout-head.pr-6 {
        padding-right: 12px;
        font-size: 21px;
        line-height: 21px;
        letter-spacing: 0.18px;
    }
    #metastatic-efficacy #wrapper-container-3 .callout-wrap .callout-txt {
        font-size: 16px;
    }
    #metastatic-efficacy .callout-wrap .callout-copy p.callout-head.ls-21 {
        letter-spacing: 0.21px;
    }
    #metastatic-efficacy .key-table .table-block.sf-ar-1 th {
        font-size: 11px;
        line-height: 13px;
    }
    #metastatic-efficacy .key-table1 .table-block td, #metastatic-efficacy .key-table1 .table-block th, #metastatic-efficacy .key-table2 .table-block2 td, #metastatic-efficacy .key-table2 .table-block2 th, #metastatic-efficacy .key-table3 .table-block3 td, #metastatic-efficacy .key-table3 .table-block3 th {
        font-size: 10px;
        line-height: 11px;
        padding: 7px 10px;
    }
    #metastatic-efficacy .key-table2 .table-block2 th,
    #metastatic-efficacy .key-table3 .table-block3 th {
        font-size: 14px;
        line-height: 16px;
    }
    #metastatic-efficacy .key-table1 .table-block td:first-child, #metastatic-efficacy .key-table2 .table-block2 td:first-child, #metastatic-efficacy .key-table3 .table-block3 td:first-child {
        max-width: 200px;
    }
    #metastatic-efficacy #white-container > .container.responsivegrid:nth-of-type(2), #metastatic-efficacy #white-container > .container.responsivegrid:nth-of-type(3), #metastatic-efficacy .safety-main-section {
        border-bottom: none;
    }
    #metastatic-efficacy .box-image.key-table.key-table3 p.box-heading {
        padding-right: 35px;
    }
    #metastatic-efficacy tr:not(.span-row) td:first-child::after {
        content: '';
        width: 1px;
        position: absolute;
        height: 100%;
        background: #b5cef2;
        top: 0;
        right: -1px;
        box-shadow: 0px 3px 6px #00000067;
    }
    #metastatic-efficacy .box-image img {
        max-width: 323px;
        margin: 18px auto 10px;
        width: 323px;
    }
    #metastatic-efficacy .os-iit-subgroup-img .table-block th:last-child img {
        max-width: 596px;
        width: auto;
        margin-top: 0;
    }
    #metastatic-efficacy td:first-child:after, #metastatic-efficacy th:first-child:after {
        content: '';
        width: 1px;
        position: absolute;
        height: 100%;
        background: #b5cef2;
        top: 0;
        right: -1px;
        box-shadow: 0px 3px 6px #00000067;
    }
    #metastatic-efficacy .os-iit-subgroup-img .table-block th, 
    #metastatic-efficacy .os-pd-l1-img .table-block th {
        padding: 0;
        border: none;
    }
    #metastatic-efficacy .table-block, #metastatic-efficacy .table-block2 {
        margin: 20px auto 5px;
        max-width: 615px;
    }
    #metastatic-efficacy .ef-anchor-sec {
        margin-top: 3px;
    }
    #metastatic-efficacy .box-image.os-kras-img img, #metastatic-efficacy .box-image.os-pd-l1-img img {
        padding-top: 0;
        max-width: 331px;
        margin: 0 auto;
        margin-top: 10px;
        width: 100%;
    }
    #metastatic-efficacy #white-container > .container.responsivegrid:nth-of-type(2), #metastatic-efficacy #white-container > .container.responsivegrid:nth-of-type(3), #metastatic-efficacy #white-container > .container.responsivegrid:nth-of-type(4), #metastatic-efficacy #white-container > .container.responsivegrid:nth-of-type(5), #metastatic-efficacy #white-container > .container.responsivegrid:nth-of-type(6), #metastatic-efficacy #white-container > .container.responsivegrid:nth-of-type(7), #metastatic-efficacy #white-container > .container.responsivegrid:nth-of-type(8), #metastatic-efficacy .safety-main-section {
        border-bottom: none;
    }
    #metastatic-efficacy .box-image.os-skt-img img {
        padding: 0;
    }
    /* #metastatic-efficacy p.footnotes.pb-25 {
        padding-bottom: 0;
    } */
    #metastatic-efficacy .table-block2 th, #metastatic-efficacy .table-block2 td {
        border-bottom: none;
        padding: 0;
    }
    #metastatic-efficacy .table-block2.mobile-only th:last-child img {
        max-width: 509px;
    }
    #metastatic-efficacy .anchoring-section.last-divider .pos-eff-links {
        margin-bottom: 5px;
    }
    #metastatic-efficacy #sec-3-tab-1 p.footnotes.pb-25,
    #metastatic-efficacy #sec-3-tab-2 p.footnotes.pb-25,
    #metastatic-efficacy #sec-3-tab-3 p.footnotes.pb-25 {
        padding-bottom: 0px;
    }
    #metastatic-efficacy #sec-4-tab-1 p.box-heading.s-line {
        padding-bottom: 0;
    }
    #metastatic-efficacy #sec-1-tab-2 .cmp-title__text, #metastatic-efficacy #sec-1-tab-3 .cmp-title__text, #metastatic-efficacy #sec-2-tab-3 .cmp-title__text, #metastatic-efficacy #sec-3-tab-3 .cmp-title__text, #metastatic-efficacy #sec-4-tab-1 .cmp-title__text {
        margin-top: 20px;
    }
    #metastatic-efficacy .box-image.box-image--circles .eyebrow.mt-10 {
        margin-top: 10px;
    }
    #metastatic-efficacy .box-image.box-image--circles .prevalence img {
        width: 209.103px;
        height: 245.72px;
        margin: 10px 0 20px;
    }
    #metastatic-efficacy .box-image.box-image--circles .prevalence .prevalence-contnet {
        margin-top: 0;
    }
    #metastatic-efficacy .box-image.box-image--circles .prevalence .prevalence-contnet p:first-of-type {
        margin-bottom: 10px;
    }
    #metastatic-efficacy .per-block {
        padding: 15px 15px 17px 23px;
        margin-bottom: 20px;
    }
    #metastatic-efficacy #main-container .per-block h2 {
        padding: 0 0px 0 80px;
        text-box: cap alphabetic;
    }
    #metastatic-efficacy #main-container #keap1-title h2 {
        margin-top: 16px;
    }
    #metastatic-efficacy #main-container #kras-title h2 {
        margin-top: 16px;
    }
    #metastatic-efficacy .box-image.os-keap1-img p.box-heading.s-line {
        max-width: 270px;
        margin-left: 15px;
        padding-left: 5px;
        width: 100%;
        margin-right: 23px;
        padding-right: 0;
    }
    #metastatic-efficacy .box-image.os-keap1-img img {
        margin: 0 auto;
        max-width: 332px;
        width: 100%;
        padding-bottom: 0;
    }
    #metastatic-efficacy .spacer {
        padding-bottom: 0;
        display: block;
    }
    #metastatic-efficacy .box-image .data-compare .data-num span {
        font-size: 34px;
        line-height: normal;
        letter-spacing: 0;
        display: block;
        margin: 0 0 5px 9px;
    }
    #metastatic-efficacy .box-image .data-compare .data-content {
        font-size: 16px;
        line-height: normal;
    }
    #metastatic-efficacy #sec-4-tab-1 .box-contains-txt {
        display: none;
    }
    #metastatic-efficacy ol.cmp-tabs__tablist .cmp-tabs__tab.cmp-tabs__tab--active, #metastatic-efficacy ol.cmp-tabs__tablist .cmp-tabs__tab:hover {
        text-decoration: underline 3px solid #AC172D;
        text-underline-offset: 13.5px;
        border-bottom: 0;
        font-weight: 700;
    }
    #metastatic-efficacy .box-image.os-kras-img p.box-heading.s-line {
        margin-left: 15px;
        width: 92%;
        padding-left: 5px;
        padding-right: 0;
        margin-right: 23px;
    }

    /*Study design*/
    #metastatic-efficacy .hscroll-bar,
    #metastatic-efficacy .hscroll-bar2,
    #metastatic-efficacy .hscroll-bar3 {
        margin-top: 30px;
        overflow: auto;
        white-space: nowrap;
        transform: rotate(180deg);
        margin-bottom: 10px;
        border: 1px solid #808184;
        width: 299px;
        margin-left: auto;
        margin-right: auto;
    }
    #metastatic-efficacy .hscroll-bar .hscroll-thumb,
    #metastatic-efficacy .hscroll-bar2 .hscroll-thumb2,
    #metastatic-efficacy .hscroll-bar3 .hscroll-thumb3 {
        background: #ffffff;
        height: 11px;
        position: relative;
    }
    #metastatic-efficacy .hscroll-bar .hscroll-thumb span,
    #metastatic-efficacy .hscroll-bar2 .hscroll-thumb2 span,
    #metastatic-efficacy .hscroll-bar3 .hscroll-thumb3 span {
        position: absolute;
        height: 11px;
        background: #808184;
    }
    #metastatic-efficacy .table-block,
    #metastatic-efficacy .table-block2,
    #metastatic-efficacy .table-block3 {
        overflow: scroll;
    }
    #metastatic-efficacy .hr-scroll-txt p {
        font-weight: 700;
        font-size: 14px;
        line-height: 16px;
        letter-spacing: 0.03px;
        position: relative;
        color: #4a4a4a;
        margin: 0 0 10px;
        text-align: center;
    }
    #metastatic-efficacy .hr-scroll-txt p:after {
        padding-left: 3px;
        padding-top: 1px;
        content: '\f054';
        font-family: 'icomoon';
        font-weight: 100;
        font-size: 13px;
        position: absolute;
        -webkit-text-stroke: 1px #fff;
        display: none;
    }
    #metastatic-efficacy td:first-child, #metastatic-efficacy th:first-child {
        position: sticky;
        left: 0;
        background: #ffffff;
        z-index: 1;
    }
    #metastatic-efficacy .tbl-adverse-reactions .span-row td:nth-child(1) {
        width: 204px;
        max-width: 204px;
        display: block;
        padding: 7px 10px;
    }
    #metastatic-efficacy .ds-btc.table-block th {
        white-space: nowrap;
        font-size: 13px;
        line-height: 15px;
    }
    #metastatic-efficacy .ds-btc.table-block td {
        white-space: nowrap;
        font-size: 13px;
        line-height: 15px;
        padding: 7px 32px;
    }
    #metastatic-efficacy .ds-btc.table-block2 th, #metastatic-efficacy .ds-btc.table-block2 td {
        white-space: nowrap;
        font-size: 12px;
        line-height: 13px;
        padding-right: 10px;
        padding-left: 10px;
    }
    #metastatic-efficacy .tbl-adverse-reactions .span-row td:nth-child(2), #metastatic-efficacy .tbl-adverse-reactions .span-row td:nth-child(3) {
        padding: 7px 20px;
    }
    #metastatic-efficacy .table-block::-webkit-scrollbar, #metastatic-efficacy .hscroll-bar::-webkit-scrollbar,
    #metastatic-efficacy .table-block2::-webkit-scrollbar, #metastatic-efficacy .hscroll-bar2::-webkit-scrollbar,
    #metastatic-efficacy .table-block3::-webkit-scrollbar, #metastatic-efficacy .hscroll-bar3::-webkit-scrollbar {
        display: none;
    }
    #metastatic-efficacy .arrow-callout {
        padding: 18px 8px 18px 30px;
        margin: 0px 0 25px auto;
        margin-top: 15px;
    }
    #metastatic-efficacy .arrow-callout p {
        font-size: 16px;
        line-height: 18px;
    }
    #metastatic-efficacy .arrow-callout:before {
        width: 42px;
        height: 25px;
    }
    #metastatic-efficacy .box-top-content .box-wrap .box-txt .fw-light {
        font-weight: 400;
        font-size: 10px;
        line-height: 14px;
    }
    #metastatic-efficacy .box-image.key-table.key-table2 .box-heading {
        padding: 0px 10px 10px 15px;
        padding-right: 0;
        letter-spacing: -0.6px;
        max-width: 100%;
        width: 265px;
    }
    #metastatic-efficacy .patients-permanently-discontinued {
        padding: 10px 10px 10px 17px;
    }
    #metastatic-efficacy .patients-permanently-discontinued h2 {
        margin: 0 0 10px;
    }
    #metastatic-efficacy .tbl-adverse-reactions td.span-cell.pl-5.tb-3, 
    #metastatic-efficacy .laboratory-abnormalities td.span-cell.pl-5.tb-3 {
        padding-top: 10px;
        padding-bottom: 10px;
    }
    #metastatic-efficacy .arrow-list li:before {
        content: '';
        background: url(/content/dam/intelligentcontent/brands/imfinzi-hcp/us/en/nsclc/metatastic/efficacy/images/list-arrow.svg) no-repeat;
        position: absolute;
        width: 26px;
        height: 13px;
        top: 3px;
        left: -33px;
        background-size: 100%;
    }
    #metastatic-efficacy .ds-btc.table-block2.laboratory-abnormalities tr:nth-child(7) td {
        height: 23px !important;
    }
    #metastatic-efficacy .ds-btc.table-block2.laboratory-abnormalities tr:nth-child(8) td {
        white-space: normal;
    }
    #metastatic-efficacy .laboratory-abnormalities .border-r-b-none.bb-none th {
        height: 35px;
    }
    #metastatic-efficacy .laboratory-abnormalities .border-r-b-none th {
        height: 35.5px;
    }
    #metastatic-efficacy .ds-btc.table-block2.laboratory-abnormalities td {
        height: auto;
        padding-top: 4.5px;
        padding-bottom: 4.5px;
    }
    #metastatic-efficacy .ds-btc.table-block2.laboratory-abnormalities th.clr-blue.h34 {
        padding-right: 50px;
    }

    #metastatic-efficacy ol.cmp-tabs__tablist .cmp-tabs__tab:not(:last-child)::after {
        right: -10px;
    }
    #metastatic-efficacy .box-image.box-image--circles .prevalence {
        flex-direction: column;
    }


    /*Hot Link*/
    #metastatic-efficacy .safety-page-content {
        margin: 0 15px;
    }
    #metastatic-efficacy .switch-section {
        width: 90%;
        margin: 0px auto 0px;
    }
    #metastatic-efficacy .switch-section a {
        font-size: 16px;
        line-height: 20px;
    }
    #metastatic-efficacy .switch-section a.home-link {
        padding: 30px 15px 30px 40px;
    }
    #metastatic-efficacy .switch-section a.safety-link {
        padding: 30px 40px 30px 0px;
    }

    /*ISI*/
    #metastatic-efficacy .dmmr-isi {
        margin-top: 10px;
    }
    #metastatic-efficacy .sticky-isi #sticky-isi .see-indication-container.active .see-full-container {
        height: calc(100vh - 226px);
    }
    #metastatic-efficacy .sticky-isi #sticky-isi .see-full-container .page-content p {
        padding: 0 23px 9px 10px;
        letter-spacing: -0.3px;
    }
    #metastatic-efficacy .section-isi .left-isi h2 {
        font-size: 20px;
    }
    #metastatic-efficacy .dmmr-footer .reference-section {
        padding: 0 35px 0 15px;
    }
}