#muscle-invasive.muscle-invasive-bladder-cancer #lightbox-home-first,
#muscle-invasive.muscle-invasive-bladder-cancer #lightbox-home-second,
#muscle-invasive.muscle-invasive-bladder-cancer #lightbox-home-third,
#muscle-invasive.muscle-invasive-bladder-cancer .lightbox {
  box-sizing: border-box;
  width: 736px;
}

#muscle-invasive.muscle-invasive-bladder-cancer #lightbox-home-first,
#muscle-invasive.muscle-invasive-bladder-cancer #lightbox-home-second,
#muscle-invasive.muscle-invasive-bladder-cancer #lightbox-home-third {
  margin-bottom: 30px;
}

#muscle-invasive.muscle-invasive-bladder-cancer .lightbox,
#muscle-invasive.muscle-invasive-bladder-cancer .lightbox * {
  box-sizing: border-box;
}

#muscle-invasive.muscle-invasive-bladder-cancer .lightbox {
  background-image: linear-gradient(#03315d, #03315d);
  background-position: 345px 12px;
  background-repeat: no-repeat;
  background-size: calc(100% - 345px) 1px;
  color: #003865;
  font-family: Ubuntu;
  height: 362px;
  padding: 0;
  position: relative;
}

#muscle-invasive.muscle-invasive-bladder-cancer .lightbox::after {
  background: #003262;
  bottom: 1px;
  content: "";
  left: 0;
  position: absolute;
  top: 4px;
  width: 10px;
}

#muscle-invasive.muscle-invasive-bladder-cancer .lightbox__eyebrow {
  color: #003865;
  font-family: Ubuntu;
  font-size: 14px;
  font-weight: 700;
  left: 17px;
  line-height: 18px;
  margin: 0;
  position: absolute;
  top: 3px;
  width: 350px;
}

#muscle-invasive.muscle-invasive-bladder-cancer .lightbox__eyebrow sup {
  color: #003865;
  font-family: Ubuntu;
  font-size: 7px;
  font-weight: 700;
  line-height: 0;
  vertical-align: super;
}
#muscle-invasive__dosing .gem-blw-text {
  font-size: 16px;
  color: #555;
  font-family: "Ubuntu", sans-serif;
  font-weight: 700;
}
#muscle-invasive.muscle-invasive-bladder-cancer .lightbox__box {
  border-bottom: 1px solid #03315d;
  border-bottom-right-radius: 28px;
  border-right: 1px solid #03315d;
  display: flex;
  flex-direction: column;
  height: 349px;
  left: 0;
  padding: 31px 11px 14px 31px;
  position: absolute;
  top: 12px;
  width: 736px;
}

#muscle-invasive.muscle-invasive-bladder-cancer .lightbox__question {
  color: #ad1f2f;
  font-family: Ubuntu;
  font-size: 28px;
  font-weight: 700;
  line-height: 28px;
  left: auto;
  margin: 0;
  position: static;
  top: auto;
  width: 692px;
}

#muscle-invasive.muscle-invasive-bladder-cancer .lightbox__content {
  display: flex;
  gap: 24px;
  left: auto;
  margin-top: 43px;
  position: static;
  top: auto;
}

#muscle-invasive.muscle-invasive-bladder-cancer .lightbox__media {
  flex: 0 0 201px;
  left: auto;
  position: static;
  top: auto;
}

#muscle-invasive.muscle-invasive-bladder-cancer .lightbox__metric {
  left: auto;
  margin-left: 24px;
  position: static;
  top: auto;
  width: 151px;
}

#muscle-invasive.muscle-invasive-bladder-cancer .lightbox__metric-image {
  display: block;
  height: auto;
  margin: 0;
  width: 100%;
}

#muscle-invasive.muscle-invasive-bladder-cancer .lightbox__note {
  color: #555;
  font-family: Ubuntu;
  font-size: 12px;
  font-weight: 400;
  left: auto;
  line-height: 14px;
  margin: 16px 0 0;
  position: static;
  top: auto;
  width: 201px;
}

#muscle-invasive.muscle-invasive-bladder-cancer .lightbox__main {
  display: flex;
  flex: 0 0 464px;
  flex-direction: column;
  left: auto;
  position: static;
  top: auto;
}

#muscle-invasive.muscle-invasive-bladder-cancer .lightbox__title {
  color: #003865;
  font-family: Ubuntu;
  font-size: 24px;
  font-weight: 700;
  line-height: 22px;
  margin: 0 0 5px;
  position: static;
}

#muscle-invasive.muscle-invasive-bladder-cancer .lightbox__copy {
  color: #003865;
  font-family: Ubuntu;
  font-size: 16px;
  font-weight: 500;
  line-height: 20px;
  margin: 0;
  position: static;
}

#muscle-invasive.muscle-invasive-bladder-cancer .lightbox__copy--strong {
  color: #003865;
  font-weight: 700;
}

#muscle-invasive.muscle-invasive-bladder-cancer .lightbox__copy--secondary {
  color: #555;
  font-family: Ubuntu;
  font-size: 16px;
  font-weight: 400;
  line-height: 20px;
  margin-top: 4px;
}

#muscle-invasive.muscle-invasive-bladder-cancer .lightbox__button {
  align-items: center;
  align-self: flex-start;
  background: #07729b;
  border: 2px solid #07729b;
  border-bottom-right-radius: 16px;
  color: #fff;
  display: flex;
  font-family: Ubuntu;
  font-size: 18px;
  font-weight: 700;
  height: 41px;
  justify-content: center;
  left: auto;
  line-height: 1;
  margin-top: 6px;
  min-width: 164px;
  padding: 0 16px;
  position: static;
  text-decoration: none;
  top: auto;
  width: auto;
}

#muscle-invasive.muscle-invasive-bladder-cancer .lightbox__button:hover {
  background-color: #fff;
  border-color: #07729b;
  color: #07729b;
  outline: none;
  text-decoration: none;
}

#muscle-invasive.muscle-invasive-bladder-cancer .lightbox sup {
  color: inherit;
  font-family: system-ui;
}

#muscle-invasive.muscle-invasive-bladder-cancer
  .lightbox
  .lightbox__eyebrow
  sup {
  color: #003865;
  font-family: Ubuntu;
  font-size: 7px;
  font-weight: 700;
  line-height: 0;
  vertical-align: super;
}

#muscle-invasive.muscle-invasive-bladder-cancer .lightbox em {
  color: inherit;
  font-family: inherit;
  font-size: inherit;
  font-style: italic;
  font-weight: inherit;
  line-height: inherit;
}

#muscle-invasive.muscle-invasive-bladder-cancer .quote,
#muscle-invasive.muscle-invasive-bladder-cancer .quote * {
  box-sizing: border-box;
}

#muscle-invasive.muscle-invasive-bladder-cancer .quote {
  color: #003865;
  font-family: Ubuntu;
  margin: 0 0 20px;
  max-width: 1053px;
  width: 100%;
}

#muscle-invasive.muscle-invasive-bladder-cancer .quote__text {
  color: #003865;
  font-family: Ubuntu;
  font-size: 24px;
  font-weight: 700;
  line-height: 25px;
  margin: 0;
  max-width: 740px;
}

#muscle-invasive.muscle-invasive-bladder-cancer .quote__highlight {
  color: #ad1f2f;
}

#muscle-invasive.muscle-invasive-bladder-cancer .quote__attribution {
  color: #003865;
  display: inline;
  font-family: Ubuntu;
  font-size: 20px;
  font-style: italic;
  font-weight: 400;
  line-height: 16px;
  margin: 0;
  max-width: 740px;
  padding: 0 0 0 0.5rem;
}

#muscle-invasive.muscle-invasive-bladder-cancer .nccn-footnotes {
  margin: 0 0 15px;
}

#muscle-invasive__efficacy #efficacy-main-container .nccn-footnotes {
  padding-left: 0;
}

#muscle-invasive__efficacy #efficacy-main-container .nccn-footnotes p {
  padding-left: 0;
}

.muscle-invasive-bladder-cancer h3.headline-landing {
  margin: 0 0 30px;
  padding: 0;
  font-family: Ubuntu;
  font-size: 38px;
  font-style: normal;
  font-weight: 700;
  line-height: 48px;
  color: #003865;
}

.muscle-invasive-bladder-cancer span.heading-landing--emphasis {
  font-size: 48px;
  line-height: 48px;
}

#muscle-invasive__safety .title h1,
#muscle-invasive__dosing .title h1,
#muscle-invasive__moa .title h1 {
  background: transparent;
  padding: 70px 0 0 55px;
  font-size: 24px;
  font-style: normal;
  font-weight: 500;
  line-height: normal;
  color: #003865;
  margin: 0 0 10px;
}

#muscle-invasive__dosing #dosing-main-container .title h1,
#muscle-invasive__moa #moa-main-container .title h1 {
  padding: 70px 0 0 55px;
  margin: 0 0 10px;
}

#muscle-invasive__moa .title h1,
#muscle-invasive__moa #moa-main-container .title h1 {
  background: transparent !important;
  color: #003865 !important;
  font-family: Ubuntu, sans-serif !important;
  font-size: 24px !important;
  font-style: normal !important;
  font-weight: 500 !important;
  line-height: normal !important;
  margin: 0 0 10px !important;
  padding: 70px 0 0 55px !important;
  text-align: left !important;
}

#muscle-invasive__efficacy .title h1 {
  margin: 0 auto;
}

#muscle-invasive__dosing #grey-head,
#muscle-invasive__moa #grey-head {
  background: #fff;
  font-family: Ubuntu, sans-serif;
  margin: 0 auto;
  max-width: 773px;
}

#muscle-invasive__dosing #dosing-main-container h3.headline-landing,
#muscle-invasive__moa #moa-main-container h3.headline-landing {
  background: transparent;
  border: 0;
  color: #003865;
  font-family: Ubuntu;
  font-size: 48px;
  font-style: normal;
  font-weight: 700;
  line-height: 48px;
  margin: 0 0 30px;
  padding: 0;
}

#muscle-invasive__dosing #dosing-main-container span.heading-landing--emphasis,
#muscle-invasive__moa #moa-main-container span.heading-landing--emphasis {
  background: transparent;
  color: inherit;
  display: inline;
  font-size: 48px;
  font-weight: 700;
  line-height: 48px;
  padding: 0;
}

#muscle-invasive__dosing #grey-head p,
#muscle-invasive__moa #grey-head p {
  color: #555;
  font-family: Ubuntu;
  font-size: 18px;
  font-weight: 700;
  line-height: 28px;
  margin: 10px 0 30px;
}

#muscle-invasive__moa #moa-main-container .title + .text + .container {
  background: #fff;
  clear: both;
  display: block;
  float: none;
  font-family: Ubuntu, sans-serif;
  margin: 0 auto 59px;
  max-width: 888px;
}

#muscle-invasive__moa #moa-main-container .title + .text + .container::before {
  border-top: 1px solid #003865;
  box-sizing: border-box;
  content: "";
  display: block;
  height: 10px;
  width: 100%;
}

#muscle-invasive__moa
  #moa-main-container
  .title
  + .text
  + .container
  .cmp-container {
  margin: 0 auto;
  max-width: 773px;
}

#muscle-invasive__efficacy h3.headline-update {
  color: #ac182e;
  font-family: "Ubuntu";
  font-size: 28px;
  font-weight: 700;
  margin: 0 0 10px;
}

#muscle-invasive__dosing
  #dosing-main-container
  #preparation-storage
  h3.headline-update,
#muscle-invasive__dosing
  #dosing-main-container
  #preparation-storage
  .cmp-text
  h3.headline-update {
  color: #003865;
  font-family: "Ubuntu";
  font-size: 28px;
  font-weight: 700;
  margin: 30px 0 0;
}

#muscle-invasive__efficacy #efs-section h3.headline-update {
  margin: 30px 0 0;
}

#muscle-invasive__efficacy #efs-section h3.headline-var--sub.headline2 {
  margin-bottom: 40px;
}

#muscle-invasive__efficacy #efs-section h3.headline-update--var2 {
  margin: 0;
}

#muscle-invasive__efficacy #efs-section ul.list-update--var1 {
  margin-bottom: 20px !important;
}

#muscle-invasive__efficacy #efficacy-main-container .surgicalTitle {
  color: #ac182e;
  font-family: "Ubuntu";
  font-size: 28px;
  font-weight: 700;
}

#muscle-invasive__efficacy #study-design h3.headline-update {
  margin: 30px 0 0;
}

#muscle-invasive__efficacy #key-points {
  scroll-margin-top: 160px;
}

#muscle-invasive__safety #key-points,
#muscle-invasive__dosing #key-points,
#muscle-invasive__moa #key-points {
  scroll-margin-top: 160px;
}

#muscle-invasive__efficacy
  #efficacy-main-container
  .update-prominent
  .headline-var--sub.estimatedOS {
  color: #003865;
  font-size: 22px;
  font-weight: 500;
}

#muscle-invasive__efficacy
  #efficacy-main-container
  #study-design
  > .button
  + .text
  .headline-var {
  padding: 30px 0 0 !important;
}

#muscle-invasive__efficacy #efficacy-main-container .update-prominent .list li {
  font-size: 18px;
}

.muscle-invasive-bladder-cancer .jumplink-btn,
.muscle-invasive-bladder-cancer .jumplink-btn * {
  box-sizing: border-box;
}

.muscle-invasive-bladder-cancer .jumplink-btn {
  align-items: center;
  background: #ad1f2f;
  border: 1px solid #ad1f2f;
  border-bottom-right-radius: 16px;
  box-shadow: 0 0 6px rgba(0, 0, 0, 0.5);
  color: #fff;
  display: inline-flex;
  font-family: Ubuntu;
  height: 45px;
  line-height: 1;
  max-width: 100%;
  padding: 5px 16px 5px 11px;
  text-decoration: none;
  visibility: visible;
  width: 246px;
}

.muscle-invasive-bladder-cancer .jumplink-btn:hover,
.muscle-invasive-bladder-cancer .jumplink-btn:focus-visible {
  background: #fff;
  color: #ad1f2f;
  outline: none;
  text-decoration: none;
}

#muscle-invasive__safety.muscle-invasive-bladder-cancer .jumplink-btn {
  /*width: 360px;*/
  width: 260px;
}

.muscle-invasive-bladder-cancer .jumplink-btn__icon {
  display: block;
  flex: 0 0 29.43px;
  height: 35px;
  margin-right: 9.99px;
  visibility: visible;
  width: 29.43px;
}

.muscle-invasive-bladder-cancer .jumplink-btn__label {
  align-items: baseline;
  color: currentColor;
  display: inline-flex;
  flex: 1 1 auto;
  font-size: 16px;
  line-height: 1;
  min-width: 0;
  white-space: nowrap;
}

.muscle-invasive-bladder-cancer .jumplink-btn__label-prefix {
  font-weight: 400;
  margin-right: 4px;
}

.muscle-invasive-bladder-cancer .jumplink-btn__label-strong {
  font-weight: 700;
  text-transform: uppercase;
}

.muscle-invasive-bladder-cancer .jumplink-btn__chevron {
  border-color: currentColor;
  border-style: solid;
  border-width: 0 3px 3px 0;
  display: block;
  flex: 0 0 11px;
  height: 11px;
  margin-left: 8px;
  transform: rotate(45deg) translateY(-2px);
  visibility: visible;
  width: 11px;
}

#muscle-invasive__efficacy div#keypoints-jumplink,
#muscle-invasive__safety div#keypoints-jumplink,
#muscle-invasive__dosing div#keypoints-jumplink,
#muscle-invasive__moa div#keypoints-jumplink {
  margin-right: auto !important;
  max-width: 773px;
  margin: 0 auto;
  padding: 20px 0 30px;
}

#muscle-invasive__safety #grey-head p {
  margin-bottom: 20px;
}

#muscle-invasive__dosing #dosing-main-container .title + .text {
  background: #fff;
}

#muscle-invasive__moa #moa-main-container .title + .text {
  background: #fff;
  display: block;
  float: none;
  margin: 0 auto;
  max-width: 888px;
  position: relative;
  top: 0;
}

#muscle-invasive__dosing #dosing-main-container .title + .text + .container {
  clear: both;
  padding-top: 13px;
}

#muscle-invasive__safety div#keypoints-jumplink,
#muscle-invasive__dosing div#keypoints-jumplink,
#muscle-invasive__moa div#keypoints-jumplink {
  padding: 0 0 20px;
}

#muscle-invasive__moa div#keypoints-jumplink {
  padding-bottom: 43px;
}

#muscle-invasive__safety #discontinuation-rates h3.headline-update {
  color: #003865;
  font-family: "Ubuntu";
  font-size: 28px;
  font-weight: 700;
  margin: 30px 0 20px;
}

#muscle-invasive__safety h3.headline-update {
  color: #003865;
  font-family: "Ubuntu";
  font-size: 28px;
  font-weight: 700;
  margin: 0 0 20px;
}

#muscle-invasive__safety #laboratory-abnormalities h3.headline-update {
  margin-bottom: 40px;
}

#muscle-invasive__safety #safety-main-container #discontinuation-rates h2 {
  margin: 0 0 45px !important;
}

#muscle-invasive__safety
  #safety-main-container
  #laboratory-abnormalities
  .button
  + .text
  .cmp-text {
  margin-top: 30px !important;
}

#muscle-invasive__safety #discontinuation-rates .button + .text + .title {
  max-width: 773px;
}

#muscle-invasive__dosing
  #dosing-main-container
  #preparation-storage
  #key-points
  + .switch-section {
  margin-top: 0;
  padding-top: 35px;
}

#muscle-invasive__moa #moa-main-container .moa-bottom-text {
  padding-bottom: 0;
}

#muscle-invasive__moa #moa-main-container .switch-section {
  padding-top: 35px;
}

.muscle-invasive-bladder-cancer .keypoints-block,
.muscle-invasive-bladder-cancer .keypoints-block * {
  box-sizing: border-box;
}

.muscle-invasive-bladder-cancer .keypoints-block {
  background: #f1f5fa;
  border-bottom-right-radius: 30px;
  color: #555;
  font-family: Ubuntu, sans-serif;
  overflow: hidden;
  padding: 20px 30px 20px;
  position: relative;
  width: 100%;
  margin: 30px auto 30px;
}

.muscle-invasive-bladder-cancer .keypoints-block::before {
  background-color: #ad1f2f;
  /*background-image: url("/content/dam/intelligentcontent/brands/imfinzi-hcp/us/en/bladder-cancer/images/global/keypoints-block-red-bar.svg");
  background-position: 0 0;
  background-repeat: no-repeat;
  background-size: 100% 100%;*/
  content: "";
  display: block;
  height: 4px;
  left: 0;
  position: absolute;
  right: 0;
  top: 0;
}

.muscle-invasive-bladder-cancer .keypoints-block__badge {
  background-image: url("/content/dam/intelligentcontent/brands/imfinzi-hcp/us/en/bladder-cancer/images/global/keypoints-block-badge.svg");
  background-position: 0 0;
  background-repeat: no-repeat;
  background-size: 291px 57px;
  display: grid;
  height: 57px;
  margin: 0 0 20px -30px;
  width: 291px;
}

.muscle-invasive-bladder-cancer .keypoints-block__badge-label {
  grid-area: 1 / 1;
}

.muscle-invasive-bladder-cancer .keypoints-block__badge-label {
  align-self: start;
  color: #fff;
  font-family: Ubuntu, sans-serif;
  font-size: 16px;
  font-weight: 400;
  line-height: 1;
  margin: 20px 0 0 92px;
  text-transform: uppercase;
}

.muscle-invasive-bladder-cancer .keypoints-block__badge-label strong {
  font-weight: 700;
}

.muscle-invasive-bladder-cancer .keypoints-block__body {
  max-width: 712px;
}

.muscle-invasive-bladder-cancer .keypoints-block__lead,
.muscle-invasive-bladder-cancer .keypoints-block__copy {
  color: #555;
  font-family: Ubuntu, sans-serif;
  font-size: 16px;
  font-weight: 400;
  line-height: normal;
  margin: 0;
}

.muscle-invasive-bladder-cancer .keypoints-block__lead {
  margin-bottom: 20px;
}

.muscle-invasive-bladder-cancer .keypoints-block__lead strong,
.muscle-invasive-bladder-cancer .keypoints-block__copy strong {
  font-weight: 700;
}

.muscle-invasive-bladder-cancer .keypoints-block__list {
  display: grid;
  gap: 20px;
  list-style: none;
  margin: 0;
  padding: 0;
}

.muscle-invasive-bladder-cancer .keypoints-block__item {
  display: grid;
  gap: 10px;
  grid-template-columns: 16px minmax(0, 1fr);
}

.muscle-invasive-bladder-cancer .keypoints-block__item::before {
  background: #7098d2;
  border-radius: 50%;
  content: "";
  height: 6px;
  margin: 5px;
  width: 6px;
}

.muscle-invasive-bladder-cancer .keypoints-block__copy-emphasis {
  color: #ad1f2f;
  font-weight: 700;
  /* text-transform: uppercase; */
}

.muscle-invasive-bladder-cancer .keypoints-block__copy-emphasis--uppercase {
  text-transform: uppercase;
}

.muscle-invasive-bladder-cancer .keypoints-block__sublist {
  display: grid;
  gap: 10px;
  grid-column: 2 / -1;
  list-style: none;
  margin: 0;
  padding: 0;
}

.muscle-invasive-bladder-cancer .keypoints-block__subitem {
  display: grid;
  gap: 8px;
  grid-template-columns: 12px minmax(0, 1fr);
}

.muscle-invasive-bladder-cancer .keypoints-block__subitem::before {
  border: 1px solid #7098d2;
  border-radius: 50%;
  content: "";
  height: 5px;
  margin: 5px 3px;
  width: 5px;
}

.muscle-invasive-bladder-cancer .keypoints-block__footnotes {
  display: grid;
  margin: 20px 0 0 -6px;
}

.muscle-invasive-bladder-cancer .keypoints-block__footnote {
  color: #555;
  display: grid;
  font-family: Ubuntu, sans-serif;
  font-size: 12px;
  font-weight: 400;
  grid-template-columns: 7px minmax(0, 1fr);
  line-height: 12px;
  margin: 0;
}

.muscle-invasive-bladder-cancer .keypoints-block__footnote-marker,
.muscle-invasive-bladder-cancer .keypoints-block__footnote-copy {
  color: #555;
  font-family: Ubuntu, sans-serif;
  font-size: 12px;
  font-weight: 400;
  line-height: 14px;
  margin: 0;
}

#muscle-invasive__efficacy
  #key-points
  .keypoints-block__footnote
  > .keypoints-block__footnote-marker {
  box-sizing: border-box;
  padding-right: 1px;
  text-align: right;
}

#muscle-invasive__efficacy
  #key-points
  .keypoints-block__footnote
  > sup.keypoints-block__footnote-marker {
  top: 0.4em;
}

#bladder-footer .section-isi .ul-list-inner-inner > li {
  margin-left: -4px;
  text-indent: -1px;
}

#muscle-invasive__dosing.muscle-invasive-bladder-cancer .jumplink-btn {
  width: 270px;
}
#muscle-invasive__moa.muscle-invasive-bladder-cancer .jumplink-btn {
  width: 270px;
}

.muscle-invasive-bladder-cancer .section-reference .reference b {
  color: #000;
}

#muscle-invasive .content-container sup,
#muscle-invasive .section-I-footnotes sup {
  top: -0.4em;
}

#muscle-invasive__efficacy
  #efficacy-main-container
  .headline-var.headline-var1
  sup {
  top: -0.5em;
  font-size: 65%;
}

#muscle-invasive__efficacy
  #efficacy-main-container
  .footnote.footnote--content-page.footnote--hanging-symbols
  p {
  padding-left: 0;
  text-indent: -5px;
}
#muscle-invasive__efficacy
  #efficacy-main-container
  .footnote.footnote--content-page.footnote--hanging-symbols
  p:nth-child(2) {
  text-indent: -4px;
}
#muscle-invasive__efficacy
  #efficacy-main-container
  .footnote.footnote--content-page.footnote--hanging-symbols
  p:nth-child(3) {
  text-indent: -2px;
}

#muscle-invasive__efficacy
  #efficacy-main-container
  .footnote.footnote--content-page.footnote--hanging-symbols
  .footnote-symbol {
  text-indent: 0;
  width: 6px;
}

#muscle-invasive__efficacy
  #efficacy-main-container
  .footnote.footnote--content-page
  .asterisk-symbol,
#muscle-invasive__efficacy
  #efficacy-main-container
  #key-points
  .keypoints-block__footnote-marker.asterisk-symbol {
  font-size: 12.6px;
  position: relative;
  top: -0.125em;
}

#muscle-invasive__efficacy
  #efficacy-main-container
  .characteristics-table
  .tbl-baseline-char
  tbody
  > tr.td-sub
  > td:first-child {
  font-weight: 400 !important;
}

#muscle-invasive__efficacy #efficacy-main-container h3.osData {
  padding: 0 0 35px;
}

#muscle-invasive__efficacy
  #efficacy-main-container
  #surgical-data
  .table-block.sf-ar-1.new-table.content-box-image--wrapper
  td.special-cell {
  font-weight: 800 !important;
}

#muscle-invasive__efficacy sup.special-dagger {
  font-family: "Ubuntu", sans-serif;
}

#muscle-invasive__efficacy p.footnotes.p_btm_10.efficacy-footnote {
  display: block;
}

/*
 * Reusable full-chart mobile scroller. Unlike the subgroup tables, this pattern
 * scrolls the complete graphic and does not freeze a column. Add these classes
 * only to charts that should opt in to the mobile scroll treatment.
 */
.mobile-chart-scroll {
  display: none;
}

@media (max-width: 991px) {
  .mobile-chart-scroll {
    --mobile-chart-width: 100%;
    display: block;
    position: relative;
    width: 100%;
  }

  .content-box--mobile-chart-scroll > .desktop-only {
    display: none;
  }

  /* Each graph controls only its enlarged width; scroll.js handles the rest. */
  .mobile-chart-scroll--efs-km {
    --mobile-chart-width: 620px;
    padding-top: 20px;
  }

  .mobile-chart-scroll--os-secondary {
    --mobile-chart-width: 620px;
    padding-top: 20px;
  }

  .mobile-chart-scroll--efs-pcr,
  .mobile-chart-scroll--os-pcr {
    --mobile-chart-width: 620px;
    padding-top: 20px;
  }

  /* Override the legacy pCR image rule only for these opt-in curve charts. */
  .mobile-chart-scroll--efs-pcr .mobile-chart-scroll__graphic,
  .mobile-chart-scroll--os-pcr .mobile-chart-scroll__graphic {
    width: var(--mobile-chart-width) !important;
  }

  /* Opt-in table pattern: scroll every column instead of freezing the first. */
  .table-scroll--all-columns th:first-child,
  .table-scroll--all-columns td:first-child {
    left: auto !important;
    position: static !important;
    z-index: auto !important;
  }

  .table-scroll--all-columns-frame {
    isolation: isolate;
    position: relative;
    z-index: 0;
  }

  .table-scroll--all-columns-frame .table-scroll--all-columns__overlay {
    height: auto;
    left: 50%;
    opacity: 1;
    pointer-events: none;
    position: absolute;
    top: 25%;
    transform: translate(-50%, -50%);
    transition: opacity 200ms ease;
    width: 91px;
    z-index: 2;
  }

  .table-scroll--all-columns-frame.has-scrolled
    .table-scroll--all-columns__overlay {
    opacity: 0;
  }

  .table-scroll--all-columns-frame.is-not-scrollable
    .table-scroll--all-columns__overlay,
  .table-scroll--all-columns-frame.is-not-scrollable + .hscroll-bar,
  .table-scroll--all-columns-frame.is-not-scrollable
    + .hscroll-bar
    + .hr-scroll-txt {
    display: none;
  }

  .table-scroll--all-columns-frame + .hscroll-bar {
    background: #fff;
    border: 1px solid #808184;
    box-sizing: border-box;
    display: block;
    height: 10px;
    margin-bottom: 10px;
    margin-top: 20px;
    overflow: hidden !important;
    position: relative;
    transform: none !important;
    width: 100%;
  }

  .table-scroll--all-columns-frame + .hscroll-bar .hscroll-thumb {
    background: #808184;
    display: block;
    height: 100%;
    position: absolute;
    right: auto !important;
    top: 0;
    transform: none !important;
  }

  .table-scroll--all-columns-frame + .hscroll-bar .hscroll-thumb > span {
    display: none !important;
  }

  .table-scroll--all-columns-frame + .hscroll-bar + .hr-scroll-txt {
    display: block;
  }

  .table-scroll--all-columns-frame + .hscroll-bar + .hr-scroll-txt p {
    color: #808184;
    font-family: Ubuntu, sans-serif;
    font-size: 14px;
    font-style: normal;
    font-weight: 700;
    line-height: normal;
    margin: 10px 0 0;
    text-align: center;
    text-transform: uppercase;
  }

  .content-box-efs .hand-icon,
  #muscle-invasive__efficacy .content-box.exploratory-analysis .hand-icon,
  #muscle-invasive__efficacy .content-box.pcr-table .hand-icon {
    transition: opacity 200ms ease;
  }

  .content-box-efs.has-scrolled .hand-icon,
  #muscle-invasive__efficacy
    .content-box.exploratory-analysis.has-scrolled
    .hand-icon,
  #muscle-invasive__efficacy .content-box.pcr-table.has-scrolled .hand-icon {
    opacity: 0;
    pointer-events: none;
  }

    #muscle-invasive__safety .hand-icon {
    transition: opacity 200ms ease;
  }

  #muscle-invasive__safety .content-box.has-scrolled .hand-icon {
    opacity: 0;
    pointer-events: none;
  }
}

  .mobile-chart-scroll .mobile-chart-scroll__viewport {
    -webkit-overflow-scrolling: touch;
    overflow-x: auto;
    overflow-y: hidden;
    overscroll-behavior-inline: contain;
    scrollbar-width: none;
    width: 100%;
  }

  .mobile-chart-scroll .mobile-chart-scroll__viewport::-webkit-scrollbar {
    display: none;
  }

  .mobile-chart-scroll .mobile-chart-scroll__graphic {
    display: block;
    height: auto;
    max-width: none;
    width: var(--mobile-chart-width);
  }

  .mobile-chart-scroll.is-not-scrollable .mobile-chart-scroll__overlay,
  .mobile-chart-scroll.is-not-scrollable .hscroll-bar,
  .mobile-chart-scroll.is-not-scrollable .hr-scroll-txt {
    display: none;
  }

  .mobile-chart-scroll .mobile-chart-scroll__overlay {
    height: auto;
    left: 50%;
    opacity: 1;
    pointer-events: none;
    position: absolute;
    top: 42%;
    transform: translate(-50%, -50%);
    transition: opacity 200ms ease;
    width: 91px;
    z-index: 1;
  }

  .mobile-chart-scroll.has-scrolled .mobile-chart-scroll__overlay {
    opacity: 0;
  }

  .mobile-chart-scroll .hscroll-bar {
    background: #fff;
    border: 1px solid #808184;
    box-sizing: border-box;
    display: block;
    height: 10px;
    margin-bottom: 10px;
    margin-top: 20px;
    overflow: hidden;
    position: relative;
    transform: none;
    width: 100%;
  }

  .mobile-chart-scroll .hscroll-thumb {
    background: #808184;
    display: block;
    height: 100%;
    left: 0;
    position: absolute;
    top: 0;
    transform: translateX(0);
    width: 50%;
  }

  .mobile-chart-scroll .hscroll-thumb > span {
    display: none;
  }

  .mobile-chart-scroll .hr-scroll-txt {
    display: block;
  }

  .mobile-chart-scroll .hr-scroll-txt p {
    color: #808184;
    font-family: Ubuntu, sans-serif;
    font-size: 14px;
    font-style: normal;
    font-weight: 700;
    line-height: normal;
    margin: 10px 0 0;
    text-align: center;
    text-transform: uppercase;
  }
}

@media (max-width: 991px) {
  #muscle-invasive .footer-text p {
    margin-bottom: 10px;
  }

  #muscle-invasive .footer-text p:nth-of-type(2) {
    margin-bottom: 0px !important;
  }

  #muscle-invasive__efficacy
    #efficacy-main-container
    .footnote.footnote--content-page.footnote--hanging-symbols
    p {
    padding-left: 0;
  }

  #muscle-invasive__safety .title h1,
  #muscle-invasive__dosing .title h1,
  #muscle-invasive__moa .title h1 {
    font-size: 20px;
    margin-bottom: 20px;
    padding-top: 100px !important;
  }

  #muscle-invasive__dosing #dosing-main-container .title h1,
  #muscle-invasive__moa #moa-main-container .title h1 {
    font-size: 20px;
    margin: 0 0 20px;
    padding: 100px 15px 6px !important;
  }

  #muscle-invasive__moa .title h1,
  #muscle-invasive__moa #moa-main-container .title h1 {
    font-size: 20px !important;
    margin: 0 0 20px !important;
    padding: 100px 15px 6px !important;
  }

  .muscle-invasive-bladder-cancer h3.headline-landing {
    font-size: 24px;
    line-height: normal;
    margin-bottom: 20px;
  }

  .muscle-invasive-bladder-cancer span.heading-landing--emphasis {
    font-size: 26px;
    line-height: normal;
  }

  #muscle-invasive__dosing #grey-head,
  #muscle-invasive__moa #grey-head {
    max-width: calc(100% - 30px);
  }

  #muscle-invasive__dosing #dosing-main-container h3.headline-landing,
  #muscle-invasive__moa #moa-main-container h3.headline-landing {
    font-size: 26px;
    line-height: normal;
    margin-bottom: 20px;
  }

  #muscle-invasive__dosing
    #dosing-main-container
    span.heading-landing--emphasis,
  #muscle-invasive__moa #moa-main-container span.heading-landing--emphasis {
    font-size: 26px;
    line-height: normal;
  }

  #muscle-invasive__dosing #grey-head p,
  #muscle-invasive__moa #grey-head p {
    font-size: 16px;
    line-height: 20px;
    margin: 0 0 15px;
  }

  #muscle-invasive__moa #moa-main-container .title + .text + .container {
    margin: 0;
    max-width: 100%;
    padding: 0 15px;
  }

  #muscle-invasive__moa
    #moa-main-container
    .title
    + .text
    + .container::before {
    margin-left: -15px;
    width: calc(100% + 30px);
  }

  #muscle-invasive__moa .keypoints-block__footnote-marker,
  #muscle-invasive__safety .keypoints-block__footnote-marker {
    position: relative;
    right: -4px;
  }

  #muscle-invasive__moa .keypoints-block__footnote-copy,
  #muscle-invasive__safety .keypoints-block__footnote-copy {
    line-height: 14px;
  }
  #muscle-invasive__moa
    #moa-main-container
    .title
    + .text
    + .container
    .cmp-container {
    max-width: 100%;
  }

  #muscle-invasive__efficacy #key-points {
    scroll-margin-top: 120px;
  }

  #muscle-invasive__safety #key-points,
  #muscle-invasive__dosing #key-points,
  #muscle-invasive__moa #key-points {
    scroll-margin-top: 120px;
  }

  .muscle-invasive-bladder-cancer .keypoints-block {
    /*max-width: 360px;*/
    max-width: 100%;
    padding: 32px 22px 20px;
  }

  #muscle-invasive__safety div#keypoints-jumplink,
  #muscle-invasive__dosing div#keypoints-jumplink,
  #muscle-invasive__moa div#keypoints-jumplink {
    padding: 10px 0 10px;
  }

  #muscle-invasive__dosing div#keypoints-jumplink {
    padding: 0 0 7px;
  }

  #muscle-invasive__moa div#keypoints-jumplink {
    padding: 0 0 30px;
  }

  #muscle-invasive__dosing.muscle-invasive-bladder-cancer
    #dosing-main-container
    > .aem-Grid
    > .title,
  #muscle-invasive__moa.muscle-invasive-bladder-cancer
    #moa-main-container
    > .aem-Grid
    > .title {
    padding-bottom: 0 !important;
    padding-left: 15px !important;
    padding-right: 15px !important;
    padding-top: 0 !important;
  }

  #muscle-invasive__dosing.muscle-invasive-bladder-cancer
    #dosing-main-container
    > .aem-Grid
    > .title
    h1,
  #muscle-invasive__moa.muscle-invasive-bladder-cancer
    #moa-main-container
    > .aem-Grid
    > .title
    h1 {
    padding-left: 0 !important;
    padding-right: 0 !important;
  }

  #muscle-invasive__moa.muscle-invasive-bladder-cancer
    #moa-main-container
    > .aem-Grid
    > .title
    h1 {
    padding-top: 40px !important;
  }

  #muscle-invasive__safety #safety-main-container .title {
    padding: 0 15px;
  }

  #muscle-invasive__safety #safety-main-container .title h1 {
    padding-left: 0 !important;
    padding-right: 0 !important;
  }

  #muscle-invasive__safety .keypoints-block {
    margin-bottom: 0;
  }

  .muscle-invasive-bladder-cancer .keypoints-block::before {
    height: 5px;
  }

  .muscle-invasive-bladder-cancer .keypoints-block__badge {
    margin-left: -22px;
  }

  .muscle-invasive-bladder-cancer .keypoints-block__body {
    /*max-width: 316px;*/
  }

  .muscle-invasive-bladder-cancer .keypoints-block__footnotes {
    margin-left: 0;
  }

  .muscle-invasive-bladder-cancer .keypoints-block__footnote {
    grid-template-columns: 10px minmax(0, 1fr);
  }
}

#muscle-invasive.muscle-invasive-bladder-cancer .lightbox--no-eyebrow {
  background-image: none;
}

#muscle-invasive.muscle-invasive-bladder-cancer .lightbox--no-eyebrow::before {
  border-top: 1px solid #03315d;
  content: "";
  left: 10px;
  position: absolute;
  right: 0;
  top: 0;
}

#muscle-invasive.muscle-invasive-bladder-cancer .lightbox--no-eyebrow::after {
  top: 0;
}

#muscle-invasive.muscle-invasive-bladder-cancer
  .lightbox--no-eyebrow
  .lightbox__box {
  border-top: 0;
  height: 361px;
  padding-top: 43px;
  top: 0;
}

#muscle-invasive.muscle-invasive-bladder-cancer
  .lightbox--no-eyebrow
  .lightbox__box::before {
  content: none;
}

#muscle-invasive.muscle-invasive-bladder-cancer
  .lightbox--no-eyebrow
  .lightbox__content {
  align-items: flex-start;
  margin-top: 35px;
}

#muscle-invasive.muscle-invasive-bladder-cancer
  .lightbox--no-eyebrow
  .lightbox__media {
  align-items: flex-start;
  display: flex;
  flex: 0 0 201px;
  justify-content: center;
}

#muscle-invasive.muscle-invasive-bladder-cancer
  .lightbox--no-eyebrow
  .lightbox__metric {
  margin-left: 0;
  width: 151px;
}

#muscle-invasive.muscle-invasive-bladder-cancer
  .lightbox--no-eyebrow
  .lightbox__metric-image {
  height: 78px;
  width: 151px;
}

#muscle-invasive.muscle-invasive-bladder-cancer
  .lightbox--no-eyebrow
  .lightbox__main {
  flex: 0 0 464px;
}

#muscle-invasive.muscle-invasive-bladder-cancer
  .lightbox--no-eyebrow
  .lightbox__copy {
  font-size: 18px;
  font-weight: 700;
  line-height: 22px;
}

#muscle-invasive.muscle-invasive-bladder-cancer
  .lightbox--no-eyebrow
  .lightbox__button {
  height: 42px;
  margin-top: 28px;
  min-width: 309px;
}

@media (min-width: 992px) {
  #muscle-invasive.muscle-invasive-bladder-cancer
    .cmp-experiencefragment--footer
    .section-reference
    .reference,
  #muscle-invasive.muscle-invasive-bladder-cancer
    .cmp-experiencefragment--footer
    .abbrev-wrap.reference-section {
    padding-left: 5.5px;
    padding-right: 0;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer
    #lightbox-home-second
    .lightbox {
    background-position: 312px 12px;
    background-size: calc(100% - 312px) 1px;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer
    #lightbox-home-second
    .lightbox__button {
    margin-top: 45px;
  }
}

@media (min-width: 991px) {
  #muscle-invasive #main-wrapper {
    background-image: url("/content/dam/intelligentcontent/brands/imfinzi-hcp/us/en/bladder-cancer/images/desktop/Home_Hero_image_with_gradients_new.jpg");
    background-position: -111px 14px;
    background-size: 110% 82%;
  }
}

@media (max-width: 991px) {
  #muscle-invasive.muscle-invasive-bladder-cancer #lightbox-home-first,
  #muscle-invasive.muscle-invasive-bladder-cancer #lightbox-home-second,
  #muscle-invasive.muscle-invasive-bladder-cancer #lightbox-home-third,
  #muscle-invasive.muscle-invasive-bladder-cancer .lightbox {
    width: 100%;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer #lightbox-home-first,
  #muscle-invasive.muscle-invasive-bladder-cancer #lightbox-home-second,
  #muscle-invasive.muscle-invasive-bladder-cancer #lightbox-home-third {
    margin-bottom: 35px;
    margin-top: 35px;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer .lightbox {
    background-position: 100% 0;
    background-size: 19% 2px;
    height: auto;
    padding: 0;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer .lightbox::after {
    bottom: 0;
    top: 0;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer
    #lightbox-home-second
    .lightbox {
    background-size: 8% 2px;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer .lightbox--no-eyebrow::after {
    top: 0;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer .lightbox__box {
    border-bottom: 2px solid #003262;
    border-right: 2px solid #003262;
    height: auto;
    padding: 32px 9px 19px 16px;
    position: relative;
    top: 0;
    width: 100%;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer
    #lightbox-home-first
    .lightbox__box {
    padding-top: 50px;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer .lightbox__eyebrow {
    left: 17px;
    max-width: calc(100% - 34px);
    width: auto;
    top: -4px;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer .lightbox__question {
    color: #ad1f2f;
    font-family: Ubuntu;
    font-size: 24px;
    font-weight: 700;
    line-height: 26px;
    width: 100%;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer .lightbox__content {
    flex-direction: column;
    gap: 0;
    margin-top: 12px;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer
    #lightbox-home-first
    .lightbox__content,
  #muscle-invasive.muscle-invasive-bladder-cancer
    #lightbox-home-second
    .lightbox__content {
    margin-top: 15px;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer .lightbox__media,
  #muscle-invasive.muscle-invasive-bladder-cancer .lightbox__main {
    flex-basis: auto;
    width: 100%;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer .lightbox__metric {
    align-self: center;
    margin-left: 0;
    margin-bottom: 12px;
    width: 151px;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer .lightbox__note {
    color: #555;
    font-family: Ubuntu;
    font-size: 10px;
    font-weight: 400;
    line-height: 12px;
    margin: 7px 0 0;
    width: 100%;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer .lightbox__title {
    color: #003865;
    font-family: Ubuntu;
    font-size: 18px;
    font-weight: 700;
    line-height: 22px;
    margin-bottom: 7px;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer .lightbox__copy {
    color: #003865;
    font-family: Ubuntu;
    font-size: 16px;
    font-weight: 500;
    line-height: 20px;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer .lightbox__copy--strong {
    color: #003865;
    font-weight: 600;
    line-height: 17px;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer .lightbox__copy--secondary {
    color: #555;
    font-family: Ubuntu;
    font-size: 15px;
    font-weight: 400;
    line-height: 20px;
    margin-top: 7px;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer .lightbox__button {
    align-self: center;
    color: #fff;
    font-family: Ubuntu;
    font-size: 18px;
    font-weight: 700;
    height: 42px;
    line-height: 42px;
    margin-top: 19px;
    padding: 0 27px 0 18px;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer
    .lightbox:not(.lightbox--no-eyebrow)
    .lightbox__media,
  #muscle-invasive.muscle-invasive-bladder-cancer
    .lightbox:not(.lightbox--no-eyebrow)
    .lightbox__main {
    display: contents;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer
    .lightbox:not(.lightbox--no-eyebrow)
    .lightbox__metric {
    order: 1;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer
    .lightbox:not(.lightbox--no-eyebrow)
    .lightbox__title {
    order: 2;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer
    .lightbox:not(.lightbox--no-eyebrow)
    .lightbox__copy--strong {
    order: 3;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer
    .lightbox:not(.lightbox--no-eyebrow)
    .lightbox__copy--secondary {
    order: 4;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer
    .lightbox:not(.lightbox--no-eyebrow)
    .lightbox__note {
    order: 5;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer
    .lightbox:not(.lightbox--no-eyebrow)
    .lightbox__button {
    order: 6;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer .lightbox__button:hover {
    background-color: #fff;
    border-color: #07729b;
    color: #07729b;
    outline: none;
    text-decoration: none;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer
    .lightbox--no-eyebrow
    .lightbox__box {
    height: auto;
    padding: 32px 9px 19px 16px;
    top: 0;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer
    .lightbox--no-eyebrow
    .lightbox__content {
    align-items: flex-start;
    gap: 0;
    margin-top: 12px;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer
    .lightbox--no-eyebrow
    .lightbox__media,
  #muscle-invasive.muscle-invasive-bladder-cancer
    .lightbox--no-eyebrow
    .lightbox__main {
    flex-basis: auto;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer
    .lightbox--no-eyebrow
    .lightbox__copy {
    margin-top: 24px;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer
    .lightbox--no-eyebrow
    .lightbox__button {
    height: 42px;
    margin-top: 19px;
    max-width: 100%;
    min-width: 0;
    padding: 0 12px;
    text-align: center;
    white-space: nowrap;
    width: 309px;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer .quote {
    width: 100%;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer .quote__text {
    max-width: 100%;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer .quote__text {
    font-size: 21px;
    line-height: 24px;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer .quote__text br {
    display: none;
  }

  #muscle-invasive.muscle-invasive-bladder-cancer .quote__attribution {
    display: block;
    font-size: 20px;
    line-height: 16px;
    margin: 8px 0 0;
  }
}